In-vitro and in-vivo metabolism of different aspirin formulations studied by a validated liquid chromatography tandem mass spectrometry method
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89671-w
Abstract: Low-dose aspirin (ASA) is used to prevent cardiovascular events. The most commonly used formulation is enteric-coated ASA (EC-ASA) that may be absorbed more slowly and less efficiently in some patients. To uncover these “non-responders” patients,… read more here.
Keywords: vitro vivo; vivo metabolism; asa; method ... See more keywords
Can A Recently Developed Pig Model Be Used for In Vivo Metabolism Studies of 7-Azaindole Derived Synthetic Cannabinoids? A Study Using 5F-MDMB-P7AICA.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkaa122
Abstract: New psychoactive substances (NPS), especially synthetic cannabinoids (SC) remain a public health concern. Due to ethical reasons, systematic controlled human studies to elucidate their toxicodynamics and/or toxicokinetics are usually not possible. However, such knowledge is… read more here.
Keywords: vivo metabolism; pig; metabolism studies; pig model ... See more keywords
In Vivo Metabolism of 1,5-Anhydro-d-fructose to 1,5-Anhydro-d-glucitol
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DOI: 10.21873/invivo.13176
Abstract: Background/Aim: 1,5-Anhydro-d-fructose (1,5-AF, saccharide) and 1,5-anhydro-d-glucitol (1,5-AG) converted from 1,5-AF via the glycemic pathway have health benefits. However, this metabolism has not been sufficiently elucidated. To clarify the in vivo metabolism of 1,5-AF to 1,5-AG,… read more here.
Keywords: anhydro fructose; anhydro glucitol; vivo metabolism; vivo ... See more keywords
In Vivo Metabolism of [1,6-13C2]Glucose Reveals Distinct Neuroenergetic Functionality between Mouse Hippocampus and Hypothalamus
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DOI: 10.3390/metabo11010050
Abstract: Glucose is a major energy fuel for the brain, however, less is known about specificities of its metabolism in distinct cerebral areas. Here we examined the regional differences in glucose utilization between the hypothalamus and… read more here.
Keywords: 13c2 glucose; hypothalamus; metabolism; vivo metabolism ... See more keywords