Ex Vivo Models of Chronic Granulomatous Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9424-3_35
Abstract: Induced pluripotent stem cells (iPSCs) are pluripotent stem cells that can be established from dedifferentiation of all somatic cell types by epigenetic phenomena. iPSCs can be differentiated into any mature cells like neurons, hepatocytes, or… read more here.
Keywords: models chronic; granulomatous disease; chronic granulomatous; disease ... See more keywords
Critical assessment of in vitro and in vivo models to study marrow adipose tissue
Sign Up to like & getrecommendations! Published in 2020 at "Current osteoporosis reports"
DOI: 10.1007/s11914-020-00569-4
Abstract: Purpose of the Review The purpose of this review is to describe the in vitro and in vivo methods that researchers use to model and investigate bone marrow adipocytes (BMAds). Recent Findings The bone marrow… read more here.
Keywords: vivo; models study; vitro vivo; vivo models ... See more keywords
Renal ischemia/reperfusion injury: An insight on in vitro and in vivo models.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117860
Abstract: Optimal tissue oxygenation is essential for its normal function. Suboptimal oxygenation or ischemia contributes to increased mortalities during various pathological conditions such as stroke, acute kidney injury (AKI), cardiac failure. Despite the rapid progression of… read more here.
Keywords: renal ischemia; vitro vivo; vivo models; iri ... See more keywords
Perillyl Alcohol Attenuates NLRP3 Inflammasome Activation and Rescues Dopaminergic Neurons in Experimental In Vitro and In Vivo Models of Parkinson's Disease.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00550
Abstract: NLRP3 activation plays a key role in the initiation and progression of a variety of neurodegenerative diseases. However, understanding the molecular mechanisms involved in the bidirectional signaling required to activate the NLRP3 inflammasomes is the… read more here.
Keywords: inflammasome activation; vitro vivo; nlrp3 inflammasome; vivo models ... See more keywords
Efficient discrimination of transplutonium actinides by in vivo models†
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d0sc06610a
Abstract: Transplutonium actinides are among the heaviest elements whose macroscale chemical properties can be experimentally tested. Being scarce and hazardous, their chemistry is rather unexplored, and they have traditionally been considered a rather homogeneous group, with… read more here.
Keywords: transplutonium actinides; discrimination transplutonium; vivo models; actinides vivo ... See more keywords
Experimental Models and Practical Simulators for Supermicrosurgery: An Updated Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000010084
Abstract: Background: Supermicrosurgical simulators and experimental models promote test viability, a faster learning curve, technical innovations, and improvements of the surgical dexterities. The authors aimed to present a systematic review and meta-analysis of preclinical experimental models… read more here.
Keywords: experimental models; meta analysis; vivo models;
Zebrafish In Vivo Models of Cancer and Metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a037077
Abstract: Metastasis, the dispersal of cancer cells from a primary tumor to secondary sites within the body, is the leading cause of cancer-related death. Animal models have been an indispensable tool to investigate the complex interactions… read more here.
Keywords: vivo models; metastasis; models cancer; metastasis zebrafish ... See more keywords
Testicular torsion in vivo models: Mechanisms and treatments.
Sign Up to like & getrecommendations! Published in 2023 at "Andrology"
DOI: 10.1111/andr.13418
Abstract: Testicular torsion (TT) is a condition in which a testis rotates around its longitudinal axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow and perfusion of testicular… read more here.
Keywords: torsion vivo; models mechanisms; testicular torsion; vivo models ... See more keywords
In vitro and in vivo models to investigate the pathomechanisms and novel treatments for pemphigoid diseases
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Dermatology"
DOI: 10.1111/exd.13415
Abstract: Pemphigoid diseases (PD) are a subgroup of rare acute or chronic autoimmune skin disorders characterized and caused by autoantibodies directed against distinct structural components of the dermal‐epidermal junction. Binding of autoantibodies to their targets leads… read more here.
Keywords: investigate pathomechanisms; vitro vivo; vivo models; models investigate ... See more keywords
Non‐animal models of wound healing in cutaneous repair: In silico, in vitro, ex vivo, and in vivo models of wounds and scars in human skin
Sign Up to like & getrecommendations! Published in 2017 at "Wound Repair and Regeneration"
DOI: 10.1111/wrr.12513
Abstract: Tissue repair models are essential to explore the pathogenesis of wound healing and scar formation, identify new drug targets/biomarkers and to test new therapeutics. However, no animal model is an exact replicate of the clinical… read more here.
Keywords: wound healing; vivo; human skin; vivo models ... See more keywords
Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17768
Abstract: The crosstalk between immune cells, cancer cells, and extracellular vesicles (EVs) secreted by cancer cells remains poorly understood. We created three-dimensional (3D) cell culture models using human leiomyoma discs and Myogel to study the effects… read more here.
Keywords: extracellular vesicles; vitro vivo; vivo models; cells extracellular ... See more keywords