Ex Vivo Models of Chronic Granulomatous Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9424-3_35
Abstract: Induced pluripotent stem cells (iPSCs) are pluripotent stem cells that can be established from dedifferentiation of all somatic cell types by epigenetic phenomena. iPSCs can be differentiated into any mature cells like neurons, hepatocytes, or… read more here.
Keywords: models chronic; granulomatous disease; chronic granulomatous; disease ... See more keywords
Critical assessment of in vitro and in vivo models to study marrow adipose tissue
Sign Up to like & getrecommendations! Published in 2020 at "Current osteoporosis reports"
DOI: 10.1007/s11914-020-00569-4
Abstract: Purpose of the Review The purpose of this review is to describe the in vitro and in vivo methods that researchers use to model and investigate bone marrow adipocytes (BMAds). Recent Findings The bone marrow… read more here.
Keywords: vivo; models study; vitro vivo; vivo models ... See more keywords
Renal ischemia/reperfusion injury: An insight on in vitro and in vivo models.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117860
Abstract: Optimal tissue oxygenation is essential for its normal function. Suboptimal oxygenation or ischemia contributes to increased mortalities during various pathological conditions such as stroke, acute kidney injury (AKI), cardiac failure. Despite the rapid progression of… read more here.
Keywords: renal ischemia; vitro vivo; vivo models; iri ... See more keywords
Perillyl Alcohol Attenuates NLRP3 Inflammasome Activation and Rescues Dopaminergic Neurons in Experimental In Vitro and In Vivo Models of Parkinson's Disease.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00550
Abstract: NLRP3 activation plays a key role in the initiation and progression of a variety of neurodegenerative diseases. However, understanding the molecular mechanisms involved in the bidirectional signaling required to activate the NLRP3 inflammasomes is the… read more here.
Keywords: inflammasome activation; vitro vivo; nlrp3 inflammasome; vivo models ... See more keywords
A Brain-Penetrating Foldamer Rescues Aβ Aggregation-Associated Alzheimer's Disease Phenotypes in In Vivo Models.
Sign Up to like & getrecommendations! Published in 2025 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.4c00753
Abstract: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is the leading cause of dementia, affecting nearly 55 million people across the world. One of the central pathological factors associated with AD is the aggregation… read more here.
Keywords: rescues aggregation; alzheimer disease; brain; vivo models ... See more keywords
A Glucosylated BODIPY Uses the GLUT Channel to Target Cancer Cells in In Vitro and In Vivo Models
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.5c06410
Abstract: The conjugation of fluorescent probes to tumor-targeting molecules represents a promising strategy for the development of precision cancer bioimaging and treatment. Among the different tumor-targeting strategies, the use of d-glucose residues, which exploit the high… read more here.
Keywords: cancer; cancer cells; vivo models; vitro vivo ... See more keywords
Efficient discrimination of transplutonium actinides by in vivo models†
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d0sc06610a
Abstract: Transplutonium actinides are among the heaviest elements whose macroscale chemical properties can be experimentally tested. Being scarce and hazardous, their chemistry is rather unexplored, and they have traditionally been considered a rather homogeneous group, with… read more here.
Keywords: transplutonium actinides; discrimination transplutonium; vivo models; actinides vivo ... See more keywords
Ex vivo study of neuroinvasive and neurotropic viruses: what is current and what is next
Sign Up to like & getrecommendations! Published in 2025 at "FEMS Microbiology Reviews"
DOI: 10.1093/femsre/fuaf024
Abstract: Abstract Numerous pathogens, including viruses, enter the central nervous system and cause neurological disorders, such as encephalitis. Viruses are the main etiologic agents of such neurological diseases, and some of them cause a high death… read more here.
Keywords: vivo study; vivo models; vivo; neurotropic viruses ... See more keywords
Experimental Models and Practical Simulators for Supermicrosurgery: An Updated Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000010084
Abstract: Background: Supermicrosurgical simulators and experimental models promote test viability, a faster learning curve, technical innovations, and improvements of the surgical dexterities. The authors aimed to present a systematic review and meta-analysis of preclinical experimental models… read more here.
Keywords: experimental models; meta analysis; vivo models;
Zebrafish In Vivo Models of Cancer and Metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a037077
Abstract: Metastasis, the dispersal of cancer cells from a primary tumor to secondary sites within the body, is the leading cause of cancer-related death. Animal models have been an indispensable tool to investigate the complex interactions… read more here.
Keywords: vivo models; metastasis; models cancer; metastasis zebrafish ... See more keywords
Testicular torsion in vivo models: Mechanisms and treatments.
Sign Up to like & getrecommendations! Published in 2023 at "Andrology"
DOI: 10.1111/andr.13418
Abstract: Testicular torsion (TT) is a condition in which a testis rotates around its longitudinal axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow and perfusion of testicular… read more here.
Keywords: torsion vivo; models mechanisms; testicular torsion; vivo models ... See more keywords