In vivo performance of intraperitoneal onlay mesh after ventral hernia repair.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical biomechanics"
DOI: 10.1016/j.clinbiomech.2020.105076
Abstract: BACKGROUND Ventral hernia repair needs to be improved since recurrence, postoperative pain and other complications are still reported in many patients. The behavior of implants in vivo is not sufficiently understood to design a surgical… read more here.
Keywords: relative elongations; vivo performance; hernia repair; ventral hernia ... See more keywords
Coupling the in vivo performance to the in vitro characterization of PLGA microparticles.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120738
Abstract: The main objective of the study was to determine if rodent housing conditions, specifically housing climate, could impact the in vivo performance of poly(lactide-co-glycolide) (PLGA) microspheres through temperature modification of the subcutaneous space. Vivitrol®, a… read more here.
Keywords: vitro release; vitro characterization; housing; vivo performance ... See more keywords
Importance of Gastric Secretion and the Rapid Gastric Emptying of Ingested Water along the Lesser Curvature ("Magenstraße") in Predicting the In Vivo Performance of Liquid Oral Dosage Forms in the Fed State Using a Modeling and Simulation.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00778
Abstract: The objective of the present study was to develop an in silico model of the stomach for predicting oral drug absorption in fed humans. We focused on a model capable of simulating dynamic fluid volume… read more here.
Keywords: gastric emptying; fed state; secretion; vivo performance ... See more keywords
Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s181175
Abstract: Background The present study aimed to develop orlistat-loaded solid self-nanoemulsifying drug delivery system preconcentrate (SSP) with the minimum use of lipid excipients for the enhanced solubility, in vitro dissolution, lipase inhibition, and in vivo performance.… read more here.
Keywords: orlistat; enhanced solubility; orlistat loaded; vivo performance ... See more keywords