In vivo Protein Evolution, Next Generation Protein Engineering Strategy: from Random Approach to Target-specific Approach
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-018-0394-2
Abstract: In vivo protein evolution is a protein engineering approach that is performed by both generating mutagenesis libraries and selecting desired mutants in a cell. Despite its clear advantages in some aspects, the approach has not… read more here.
Keywords: protein; target specific; vivo protein; protein evolution ... See more keywords
Modeling in-vivo protein-DNA binding by combining multiple-instance learning with a hybrid deep neural network
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44966-x
Abstract: Modeling in-vivo protein-DNA binding is not only fundamental for further understanding of the regulatory mechanisms, but also a challenging task in computational biology. Deep-learning based methods have succeed in modeling in-vivo protein-DNA binding, but they… read more here.
Keywords: dna; vivo protein; protein dna; modeling vivo ... See more keywords
Visualization of in vivo protein–protein interactions in plants
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erac139
Abstract: This review aims to provide a comprehensive and critical overview of techniques used to measure protein–protein interactions in living plants. read more here.
Keywords: visualization vivo; protein protein; interactions plants; vivo protein ... See more keywords
In vivo Protein Corona Formation: Characterizations, Effects on Engineered Nanoparticles’ Biobehaviors, and Applications
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.646708
Abstract: Understanding the basic interactions between engineered nanoparticles (ENPs) and biological systems is essential for evaluating ENPs’ safety and developing better nanomedicine. Profound interactions between ENPs and biomolecules such as proteins are inevitable to occur when… read more here.
Keywords: enps; vivo protein; vivo formation; formation ... See more keywords