Combining in vitro and in vivo screening to identify efficient Pseudomonas biocontrol strains against the phytopathogenic bacterium Ralstonia solanacearum
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1283
Abstract: Although plant pathogens are traditionally controlled using synthetic agrochemicals, the availability of commercial bactericides is still limited. One potential control strategy could be the use of plant growth‐promoting bacteria (PGPB) to suppress pathogens via resource… read more here.
Keywords: vitro vivo; pathogen; ralstonia solanacearum; vivo screening ... See more keywords
Worm Generator: A System for High-Throughput in Vivo Screening.
Sign Up to like & getrecommendations! Published in 2023 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c04456
Abstract: Large-scale screening of molecules in organisms requires high-throughput and cost-effective evaluating tools during preclinical development. Here, a novel in vivo screening strategy combining hierarchically structured biohybrid triboelectric nanogenerators (HB-TENGs) arrays with computational bioinformatics analysis for… read more here.
Keywords: throughput; system high; high throughput; worm generator ... See more keywords
In vivo screening of subcutaneous tolerability for the development of novel excipients
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DOI: 10.1293/tox.2022-0035
Abstract: To develop safe subcutaneous formulations and minimize the risk of local irritation, it is essential to optimize the composition of active pharmaceutical ingredients and excipients. Depending on the physicochemical properties of the active pharmaceutical ingredient,… read more here.
Keywords: development; tolerability; active pharmaceutical; novel excipients ... See more keywords
Neisseria genes required for persistence identified via in vivo screening of a transposon mutant library
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DOI: 10.1371/journal.ppat.1010497
Abstract: The mechanisms used by human adapted commensal Neisseria to shape and maintain a niche in their host are poorly defined. These organisms are common members of the mucosal microbiota and share many putative host interaction… read more here.
Keywords: persistence; host interaction; screening transposon; host ... See more keywords
An In Vivo Screening Model for Investigation of Pathophysiology of Human Implantation Failure
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DOI: 10.3390/biom13010079
Abstract: To improve current infertility treatments, it is important to understand the pathophysiology of implantation failure. However, many molecules are involved in the normal biological process of implantation and the roles of each molecule and the… read more here.
Keywords: hvj vector; pathophysiology; implantation; implantation failure ... See more keywords