Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics
Sign Up to like & getrecommendations! Published in 2021 at "Chemmedchem"
DOI: 10.1002/cmdc.202100131
Abstract: We show the synthesis of an in vivo stable mercury compound with functionality suitable for radiopharmaceuticals. The designed cyclic bisarylmercury was based on the water tolerance of organomercurials, higher bond dissociation energy of Hg−Ph to Hg−S,… read more here.
Keywords: high chemical; vivo stability; stability; cyclic bisarylmercury ... See more keywords
Neopentyl Glycol as a Scaffold to Provide Radiohalogenated Theranostic Pairs of High In Vivo Stability.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01147
Abstract: The high in vivo stability of 2,2-dihydroxymethyl-3-[18F]fluoropropyl-2-nitroimidazole ([18F]DiFA) prompted us to evaluate neopentyl as a scaffold to prepare a radiotheranostic system with radioiodine and astatine. Three DiFA analogues with one, two, or without a hydroxyl… read more here.
Keywords: neopentyl glycol; vivo stability; labeled neopentyl; high vivo ... See more keywords
Dual-Mode Mass Spectrometric Imaging for Determination of in Vivo Stability of Nanoparticle Monolayers.
Sign Up to like & getrecommendations! Published in 2017 at "ACS nano"
DOI: 10.1021/acsnano.7b03711
Abstract: Effective correlation of the in vitro and in vivo stability of nanoparticle-based platforms is a key challenge in their translation into the clinic. Here, we describe a dual imaging method that site-specifically reports the stability… read more here.
Keywords: dual mode; mass; vivo stability; stability nanoparticle ... See more keywords
In vitro and in vivo stability of black-platinum coatings on flexible, polymer microECoG arrays.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/aacf71
Abstract: OBJECTIVE Intracranial EEG (iEEG) or micro-electrocorticography (µECoG) microelectrodes offer high spatial resolution in recordings of neuronal activity from the exposed brain surface. Reliability of dielectric substrates and conductive materials of these devices are under intensive… read more here.
Keywords: platinum; vitro vivo; black platinum; vivo stability ... See more keywords