Polyglycerolated nanocarriers with increased ligand multivalency for enhanced in vivo therapeutic efficacy of paclitaxel.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.08.042
Abstract: Despite the excellent biocompatibility and antifouling effect of poly(ethylene glycol) (PEG), the high steric hindrance, limited chemical functionality, and low ligand multivalency of PEGylated nanocarriers often lead to inefficient cell targeting and intracellular trafficking. Hence,… read more here.
Keywords: ligand multivalency; therapeutic efficacy; ligand; vivo therapeutic ... See more keywords
In vivo therapeutic effects of colorectal cancer cell-derived exosomes
Sign Up to like & getrecommendations! Published in 2020 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2020.46465.10730
Abstract: Objective(s): Exosomes are nano-sized structures with lipid bilayer membranes that can be secreted by cancer cells. They play an important role in the biology of the tumor extracellular matrix. Exosomes may contain and transfer tumor… read more here.
Keywords: colorectal cancer; cancer; cell; derived exosomes ... See more keywords