Ultrafast Z‐spectroscopic imaging in vivo at 3T using through‐slice spectral encoding (TS‐UFZ)
Sign Up to like & getrecommendations! Published in 2022 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29532
Abstract: Acquisition of high‐resolution Z‐spectra for CEST or magnetization transfer contrast (MTC) MRI requires excessive scan times. Ultrafast Z‐spectroscopy (UFZ) has been proposed to address this; however, the quality of in vivo UFZ spectra has been… read more here.
Keywords: slice spectral; imaging vivo; using slice; ultrafast spectroscopic ... See more keywords
Characterizing Semaphorin Signaling In Vivo Using C. elegans.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6448-2_34
Abstract: A small model animal Caenorhabditis elegans is particularly suitable for genetic analysis, but cell-type-specific biochemistry is a formidable task in this organism. Here we describe techniques utilizing transgenic C. elegans strains expressing epitope-tagged proteins for… read more here.
Keywords: biochemistry; vivo using; characterizing semaphorin; using elegans ... See more keywords
Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C Radiotracers
Sign Up to like & getrecommendations! Published in 2020 at "ACS Central Science"
DOI: 10.1021/acscentsci.9b00743
Abstract: Incorporation of d-amino acids into peptidoglycan is a unique metabolic feature of bacteria. Since d-amino acids are not metabolic substrates in most mammalian tissues, this difference can be exploited to detect living bacteria in vivo.… read more here.
Keywords: alanine; 11c alanine; vivo using; bacteria vivo ... See more keywords
Measurement of α-Synuclein Dynamics In Vivo Using Microdialysis with a Novel Homogeneous Immunoassay.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00251
Abstract: Understanding the regulation of α-synuclein release could be important in better understanding Parkinson's disease development, progression, and treatment. Advances in such studies are hindered by technical challenges that limit the ability to monitor α-synuclein concentration… read more here.
Keywords: measurement synuclein; synuclein; dynamics vivo; synuclein dynamics ... See more keywords
Localization of microscale devices in vivo using addressable transmitters operated as magnetic spins
Sign Up to like & getrecommendations! Published in 2017 at "Nature Biomedical Engineering"
DOI: 10.1038/s41551-017-0129-2
Abstract: The function of miniature wireless medical devices, such as capsule endoscopes, biosensors and drug-delivery systems, depends critically on their location inside the body. However, existing electromagnetic, acoustic and imaging-based methods for localizing and communicating with… read more here.
Keywords: vivo using; devices vivo; localization microscale; microscale devices ... See more keywords
Imaging of conditional gene silencing in vivo using a bioluminescence-based method with thermo-inducible microRNAs
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22932-3
Abstract: RNA interference (RNAi)-based gene therapy has great potential in cancer and infectious disease treatment to correct abnormal up-regulation of gene expression. We show a new original method uses synthetic microRNAs combined with a thermo-inducible promoter… read more here.
Keywords: vivo using; thermo inducible; imaging conditional; method ... See more keywords
Multiplexed gene silencing in living cells and in vivo using a DNAzymes-CoOOH nanocomposite.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc00822h
Abstract: We demonstrate a novel DNAzymes-based nanocomposite that can simultaneously silence three types of genes in living cells and in vivo. The synergetic strategy for silencing three different genes can significantly enhance the knockdown efficacy and… read more here.
Keywords: cells vivo; vivo using; multiplexed gene; gene silencing ... See more keywords
Monitoring ADP and ATP in vivo using a fluorescent Ga(iii)-probe complex.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc06311g
Abstract: A naphthol-based sensor (L) was designed and synthesized for the specific recognition of Ga3+ using fluorescence enhancement. An in situ generated L-Ga3+ ensemble detected ADP and ATP more selectively through a fluorescence "switch off" response,… read more here.
Keywords: vivo using; fluorescent iii; monitoring adp; adp atp ... See more keywords