In vivo visualization of enantioselective targeting of amyloid and improvement of cognitive function by clickable chiral metallohelices
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc05897a
Abstract: The pathogenesis of Alzheimer's disease (AD) is closely related to several contributing factors, especially amyloid-β (Aβ) aggregation. Bioorthogonal reactions provide a general, facile, and robust route for the localization and derivatization of Aβ-targeted agents. Herein,… read more here.
Keywords: vivo visualization; function; enantioselective targeting; cognitive function ... See more keywords
A transgenic zebrafish for in vivo visualization of cilia
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.220104
Abstract: Cilia are organelles for cellular signalling and motility. Mutations affecting ciliary function are also associated with cilia-related disorders (ciliopathies). The identification of cilia markers is critical for studying their function at the cellular level. Due… read more here.
Keywords: vivo visualization; transgenic zebrafish; visualization cilia; zebrafish vivo ... See more keywords