Genetic Variation in VKORC1 and Risk for Osteoporosis.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2020.10.008
Abstract: BACKGROUND AND AIMS The vitamin K epoxide reductase complex subunit 1 (VKORC1) plays an important role in bone development and bone metabolism by influencing the vitamin K cycle. The aim of this study was to… read more here.
Keywords: genetic variation; risk; risk osteoporosis; rs9923231 polymorphism ... See more keywords
Frequency of Common VKORC1 Polymorphisms and Their Impact on Warfarin Dose Requirement in Pakistani Population
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Applied Thrombosis/Hemostasis"
DOI: 10.1177/1076029616680478
Abstract: Polymorphisms in vitamin K epoxide reductase complex subunit 1 (VKORC1) gene lead to interindividual variability in warfarin dose requirement. The characterization of genotype frequency distribution is required in different populations for construction of customized dosing… read more here.
Keywords: vkorc1 polymorphisms; dose requirement; frequency; warfarin ... See more keywords
The potential of VKORC1 polymorphisms in Mustelidae for evolving anticoagulant resistance through selection along the food chain
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DOI: 10.1371/journal.pone.0221706
Abstract: In response to strong selection, new mutations can arise quickly and sweep through populations, particularly, if survival and reproduction depend on certain allele copies for adaptation to rapidly changing environments, like resistance against deadly diseases… read more here.
Keywords: food chain; selection; resistance; along food ... See more keywords