Vitamin K3 chloroderivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis and inhibits aggresome formation in hepatocellular carcinoma cells.
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DOI: 10.1016/j.bcp.2020.114176
Abstract: Epigenetics plays a vital role in regulating gene expression and determining the specific phenotypes of eukaryotic cells. Histone deacetylases (HDACs) are important epigenetic regulatory proteins effecting multiple biological functions. Particularly, HDAC6 has become a promising… read more here.
Keywords: vkt; huh; vkt inhibits; inhibits hdac6 ... See more keywords