X-linked myopathy with excessive autophagy due to a mutation in VMA21 gene: the first case in China
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DOI: 10.1007/s10072-021-05788-w
Abstract: Dear Editor, X-linked myopathy with excessive autophagy (XMEA) was firstly reported by Kalimo et al. in 1988 [1]. Five male patients from a Finnish family experienced proximal weakness in both lower extremities from 5–6 years… read more here.
Keywords: excessive autophagy; linked myopathy; gene; vma21 ... See more keywords
Circular RNA Derived from Vacuolar ATPase Assembly Factor VMA21 Suppresses Lipopolysaccharide-Induced Apoptosis of Chondrocytes in Osteoarthritis (OA) by Decreasing Mature miR-103 Production
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DOI: 10.1007/s12033-022-00451-x
Abstract: Circular RNA derived from vacuolar ATPase assembly factor (VMA21) has been proven to be an inflammation suppressor in many diseases, while its role in osteoarthritis (OA) is unknown. We predicted that VMA21 participates in OA… read more here.
Keywords: mir 103; apoptosis; mature mir; vma21 ... See more keywords
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.
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DOI: 10.1080/15548627.2022.2050663
Abstract: The discovery of recurrent mutations in subunits and regulators of the vacuolar-type H+-translocating ATPase (V-ATPase) in follicular lymphoma (FL) highlights a role for macroautophagy/autophagy, amino-acid, and nutrient-sensing pathways in the pathogenesis of this disease. Here,… read more here.
Keywords: chaperone vma21; follicular lymphoma; atpase; vma21 ... See more keywords