Cost-effectiveness analysis of defibrotide in the treatment of patients with severe veno-occlusive disease/sinusoidal obstructive syndrome with multiorgan dysfunction following hematopoietic cell transplantation in Spain.
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DOI: 10.1080/13696998.2021.1916749
Abstract: AIMS This study evaluated cost-effectiveness of defibrotide versus best supportive care (BSC) for the treatment of hepatic veno-occlusive disease/sinusoidal obstructive syndrome (VOD/SOS) with multiorgan dysfunction (MOD) post-hematopoietic cell transplantation (HCT) in Spain. MATERIALS AND METHODS… read more here.
Keywords: phase; patients severe; vod sos; cost ... See more keywords
Defibrotide sodium for the treatment of hepatic veno-occlusive disease/sinusoidal obstruction syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2018.1421943
Abstract: ABSTRACT Introduction: Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is an unpredictable condition associated with endothelial-cell damage due to conditioning for hematopoietic stem-cell transplantation (HSCT) or chemotherapy without HSCT. Mortality in patients with VOD/SOS and multi-organ… read more here.
Keywords: vod sos; hepatic veno; treatment; disease sinusoidal ... See more keywords
A Meta-Analysis Evaluating the Incidence of Bleeding Events With Intravenous Defibrotide Treatment Outside the Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Setting
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DOI: 10.1177/1076029620935202
Abstract: Defibrotide is approved to treat hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) with renal/pulmonary dysfunction following hematopoietic cell transplantation (HCT) in adult and pediatric patients in the United States, and to treat severe hepatic VOD/SOS post-HCT… read more here.
Keywords: defibrotide; vod sos; intravenous defibrotide; bleeding events ... See more keywords
Pooled Analysis of Defibrotide Studies in the Treatment of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT) or Chemotherapy without HSCT
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DOI: 10.1182/blood.v130.suppl_1.5467.5467
Abstract: Background VOD/SOS is an unpredictable, potentially life-threatening complication of conditioning regimens for HSCT or of chemotherapy without HSCT. VOD/SOS with multi-organ dysfunction (MOD; typically defined as renal and/or pulmonary dysfunction) may be associated with survival… read more here.
Keywords: defibrotide; vod sos; hsct; vod ... See more keywords
Timing of initiation of defibrotide (DF) post-diagnosis of hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) after hematopoietic stem cell transplantation (HSCT): Final data from an expanded-access protocol.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.7047
Abstract: 7047Background: VOD/SOS is an unpredictable, potentially life-threatening complication of HSCT. VOD/SOS with multi-organ dysfunction (MOD) may be associated with > 80% mortality. DF is approved to ... read more here.
Keywords: vod sos; defibrotide post; timing initiation; initiation defibrotide ... See more keywords