Large-scale voltage imaging in behaving mice using targeted illumination
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103263
Abstract: Summary Recent improvements in genetically encoded voltage indicators enabled optical imaging of action potentials and subthreshold transmembrane voltage in vivo. To perform high-speed voltage imaging of many neurons simultaneously over a large anatomical area, widefield… read more here.
Keywords: voltage; microscopy; illumination; behaving mice ... See more keywords
Voltage imaging identifies spinal circuits that modulate locomotor adaptation in zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2022.01.001
Abstract: Motor systems must continuously adapt their output to maintain a desired trajectory. While the spinal circuits underlying rhythmic locomotion are well described, little is known about how the network modulates its output strength. A major… read more here.
Keywords: locomotor adaptation; spinal circuits; voltage imaging;
Voltage imaging and spinal circuits get along swimmingly
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2022.03.024
Abstract: Voltage imaging promises to unite optical and electrical approaches to accelerate circuit discovery. In this issue of Neuron, Böhm et al. (2022) use voltage imaging to explore the structure and functional dynamics of spinal excitatory interneurons… read more here.
Keywords: voltage imaging; spinal circuits; get along; along swimmingly ... See more keywords
Rhodopsin-based voltage imaging tools for use in muscles and neurons of Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1902443116
Abstract: Significance Neuronal and other excitable cell activity is characterized by alteration in membrane voltage, while intracellular Ca2+ levels and transmitter release are affected downstream of electrical activity. Thus, the most direct way of monitoring neuronal… read more here.
Keywords: voltage; muscles neurons; fluorescence; caenorhabditis elegans ... See more keywords
Photoactivated voltage imaging in tissue with an archaerhodopsin-derived reporter
Sign Up to like & getrecommendations! Published in 2021 at "Science Advances"
DOI: 10.1126/sciadv.abe3216
Abstract: A photoactivated fluorescent voltage sensor protein combines high sensitivity and optical sectioning in tissue. Photoactivated genetically encoded voltage indicators (GEVIs) have the potential to enable optically sectioned voltage imaging at the intersection of a photoactivation… read more here.
Keywords: voltage; photon; imaging tissue; photoactivated voltage ... See more keywords
Bright and photostable chemigenetic indicators for extended in vivo voltage imaging
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aav6416
Abstract: Visualizing neuronal activity in vivo Imaging the changes in fluorescence of voltage-sensitive reagents would enable monitoring of the activity of neurons in vivo. Abdelfattah et al. created such a voltage indicator by designing a protein… read more here.
Keywords: voltage; bright photostable; brightness photostability; voltron ... See more keywords
Single-Neuron Level One-Photon Voltage Imaging With Sparsely Targeted Genetically Encoded Voltage Indicators
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00039
Abstract: Voltage imaging of many neurons simultaneously at single-cell resolution is hampered by the difficulty of detecting small voltage signals from overlapping neuronal processes in neural tissue. Recent advances in genetically encoded voltage indicator (GEVI) imaging… read more here.
Keywords: voltage; encoded voltage; genetically encoded; expression ... See more keywords
Imaging Voltage in Complete Neuronal Networks Within Patterned Microislands Reveals Preferential Wiring of Excitatory Hippocampal Neurons
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.643868
Abstract: Voltage imaging with fluorescent dyes affords the opportunity to map neuronal activity in both time and space. One limitation to imaging is the inability to image complete neuronal networks: some fraction of cells remains outside… read more here.
Keywords: voltage; complete neuronal; excitatory; voltage imaging ... See more keywords