Comparative Evaluation of Genetically Encoded Voltage Indicators
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2018.12.088
Abstract: SUMMARY Imaging voltage using fluorescent-based sensors could be an ideal technique to probe neural circuits with high spatiotemporal resolution. However, due to insufficient signal-to-noise ratio (SNR), imaging membrane potential in mammalian preparations is still challenging.… read more here.
Keywords: voltage; voltage indicators; photon; encoded voltage ... See more keywords
Screening and Cellular Characterization of Genetically Encoded Voltage Indicators Based on Near-Infrared Fluorescent Proteins.
Sign Up to like & getrecommendations! Published in 2020 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.0c00046
Abstract: We developed genetically encoded voltage indicators using a transmembrane voltage-sensing domain and bright near-infrared fluorescent proteins derived from bacterial phytochromes. These new voltage indicators are excited by 640 nm light and emission is measured at… read more here.
Keywords: voltage; voltage indicators; infrared fluorescent; near infrared ... See more keywords
A far-red hybrid voltage indicator enabled by bioorthogonal engineering of rhodopsin on live neurons
Sign Up to like & getrecommendations! Published in 2021 at "Nature Chemistry"
DOI: 10.1038/s41557-021-00641-1
Abstract: Membrane potential is a key aspect of cellular signalling and is dynamically regulated by an array of ion-selective pumps and channels. Fluorescent voltage indicators enable non-invasive optical recording of the cellular membrane potential with high… read more here.
Keywords: hybrid voltage; voltage; voltage indicators; indicator ... See more keywords
Optical interrogation of neuronal circuitry in zebrafish using genetically encoded voltage indicators
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23906-1
Abstract: Optical measurement of membrane potentials enables fast, direct and simultaneous detection of membrane potentials from a population of neurons, providing a desirable approach for functional analysis of neuronal circuits. Here, we applied recently developed genetically… read more here.
Keywords: voltage; voltage indicators; encoded voltage; zebrafish ... See more keywords