Design Rules for Membrane-Embedded Voltage-Sensing Nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.12.047
Abstract: Voltage-sensing dyes and voltage-sensing fluorescence proteins have been continually improved and as a result have provided a wealth of insights into neuronal circuits. Further improvements in voltage-sensing dyes and voltage-sensing fluorescence proteins are needed, however,… read more here.
Keywords: voltage; design rules; voltage sensing; rules membrane ... See more keywords
Voltage Sensing Comes to Rest
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.07.013
Abstract: Voltage sensing by ion channels is the key event enabling the generation and propagation of electrical activity in excitable cells. In this issue of Cell, Wisedchaisri et al. provide a structural view of a voltage-gated sodium… read more here.
Keywords: voltage; voltage sensing; comes rest; sensing comes ... See more keywords
Nanoscale optical voltage sensing in biological systems
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Luminescence"
DOI: 10.1016/j.jlumin.2020.117719
Abstract: Abstract Local electric fields modulate a variety of cellular processes and are particularly relevant in the nervous system. Signal propagation along an axon occurs through small (around 100 mV) rapid changes in the potential across… read more here.
Keywords: voltage; voltage sensors; voltage sensing; optical voltage ... See more keywords
A complicated complex: Ion channels, voltage sensing, cell membranes and peptide inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.04.030
Abstract: Voltage-gated ion channels (VGICs) are specialised ion channels that have a voltage dependent mode of action, where ion conduction, or gating, is controlled by a voltage-sensing mechanism. VGICs are critical for electrical signalling and are… read more here.
Keywords: ion channels; channels voltage; voltage sensing; ion ... See more keywords
Generation of heterozygous (MRli003-A-5) and homozygous (MRli003-A-6) voltage-sensing knock-in human iPSC lines by CRISPR/Cas9 editing of the AAVS1 locus.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cell research"
DOI: 10.1016/j.scr.2022.102785
Abstract: Assessment of the electrophysiological properties of cardiomyocytes is necessary for phenotyping cardiac disorders and for drug screening. Optical action potential imaging using a genetically encoded voltage-sensing fluorescent protein (VSFP) allows for high-throughput functional characterization of… read more here.
Keywords: heterozygous mrli003; voltage; locus; mrli003 homozygous ... See more keywords
The significance of electrical signals in maturing spermatozoa for phosphoinositide regulation through voltage-sensing phosphatase
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-51755-2
Abstract: Voltage-sensing phosphatase (VSP) exhibits voltage-dependent phosphatase activity toward phosphoinositides. VSP generates a specialized phosphoinositide environment in mammalian sperm flagellum. However, the voltage-sensing mechanism of VSP in spermatozoa is not yet characterized. Here, we found that… read more here.
Keywords: sensing phosphatase; voltage sensing; signals maturing; voltage ... See more keywords
What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society transactions"
DOI: 10.1042/bst20221065
Abstract: Many membrane proteins including ion channels and ion transporters are regulated by membrane phospholipids such as phosphoinositides in cell membranes and organelles. Voltage-sensing phosphatase, VSP, is a voltage-sensitive phosphoinositide phosphatase which dephosphorylates PI(4,5)P2 into PI(4)P.… read more here.
Keywords: voltage sensing; phosphatases reveal; regulation; reveal mechanisms ... See more keywords
Using single-electron box arrays for voltage sensing applications
Sign Up to like & getrecommendations! Published in 2020 at "Applied Physics Letters"
DOI: 10.1063/5.0005425
Abstract: Single-electron tunneling transistors (SETs) and boxes (SEBs) belong to the family of charge-sensitive electronic devices based on the phenomenon of Coulomb blockade. An SEB is a two-terminal device composed of “leaky,” C j, and “non-leaky,”… read more here.
Keywords: voltage; single electron; voltage sensing; using single ... See more keywords
Nonsubstrate PI(4,5)P2 interacts with the interdomain linker to control electrochemical coupling in voltage-sensing phosphatase (VSP).
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2500651122
Abstract: Voltage-sensing phosphatase (VSP) comprises a voltage sensor domain (VSD) and a cytoplasmic catalytic region (CCR), achieving a unique electrochemical signal conversion. Previous studies suggest that phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), a membrane phospholipid known to be critical… read more here.
Keywords: sensing phosphatase; voltage sensing; voltage; linker ... See more keywords
Voltage-sensing mechanism underlying the gating process of two-pore-domain potassium channels.
Sign Up to like & getrecommendations! Published in 2025 at "Physical review. E"
DOI: 10.1103/fvy1-6213
Abstract: K_{2P} channels are potassium leak channels known to play an essential role in modulating the membrane potential of neurons and glia. Their dysfunction has been associated with a wide range of diseases, including cancer, autoimmune,… read more here.
Keywords: voltage sensing; area; ion conduction; voltage ... See more keywords
Noncontact RF Voltage Sensing of a Printed Trace via a Capacitive-Coupled Probe
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Sensors Journal"
DOI: 10.1109/jsen.2018.2869908
Abstract: This paper presents a noncontact radio frequency voltage sensing of a printed trace by using a capacitive-coupled probe. The noncontact voltage sensing is demonstrated by using an open-end coaxial probe, and achieved through the transfer… read more here.
Keywords: voltage; printed trace; sensing printed; probe ... See more keywords