Utility of the von Willebrand factor collagen binding assay in the diagnosis of von Willebrand disease
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DOI: 10.1002/ajh.24556
Abstract: von Willebrand Disease (VWD) is the most common inherited bleeding disorder and also arises as an acquired defect (AVWS). VWD and AVWS are due to quantitative deficiencies and/or qualitative defects in von Willebrand factor (VWF),… read more here.
Keywords: von; collagen binding; diagnosis; von willebrand ... See more keywords
Laboratory misdiagnosis of von Willebrand disease in post‐menarchal females: A multi‐center study
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DOI: 10.1002/ajh.25869
Abstract: Increased awareness of von Willebrand Disease (VWD) has led to more frequent diagnostic laboratory testing, which insurers often dictate be performed at a facility with off‐site laboratory processing, instead of a coagulation facility with onsite… read more here.
Keywords: site; vwf; von willebrand; willebrand disease ... See more keywords
Detection of acquired von Willebrand syndrome after ventricular assist device by total thrombus‐formation analysis system
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12824
Abstract: Bleeding is a serious complication in patients with continuous‐flow left ventricular assist device (CF‐LVAD). Acquired von Willebrand syndrome (AVWS; type 2A) develops because of high shear stress inside the pumps and is a cause of… read more here.
Keywords: thrombus formation; von willebrand; system; thrombus ... See more keywords
von Willebrand factor propeptide missense variants affect anterograde transport to Golgi resulting in ER retention
Sign Up to like & getrecommendations! Published in 2021 at "Human Mutation"
DOI: 10.1002/humu.24204
Abstract: von Willebrand disease (VWD), the most prevalent congenital bleeding disorder, arises from a deficiency in von Willebrand factor (VWF), which has crucial roles in hemostasis. The present study investigated functional consequences and underlying pathomolecular mechanisms… read more here.
Keywords: missense variants; von willebrand; willebrand factor;
Feedback modulation of endothelial cells promotes epithelial‐mesenchymal transition and metastasis of osteosarcoma cells by Von Willebrand Factor release
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28875
Abstract: Endothelial cells (ECs), as a tumor niche cell, generate and secrete Von Willebrand factor (VWF) that is linked to osteosarcoma (OS) progression. However, the role and regulatory mechanisms of VWF that underpin OS progression remain… read more here.
Keywords: mesenchymal transition; epithelial mesenchymal; endothelial cells; von willebrand ... See more keywords
Two cases of von Willebrand disease type 3 in consanguineous Chinese families
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1075
Abstract: von Willebrand disease (VWD) is the most common inherited bleeding disorder caused by defective or deficient von Willebrand factor (VWF). VWD type 3 is inherited in autosomal recessive manner. We described clinical and molecular features… read more here.
Keywords: willebrand; two cases; von willebrand; type ... See more keywords
Thrombosis and von Willebrand Factor.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2016_122
Abstract: One of the key players in both hemostasis and thrombosis is von Willebrand factor (vWF), which demonstrates a duality between these two processes. Thrombus is structured by numerous elements, including endothelial cells, platelets, plasma proteins… read more here.
Keywords: vwf; thrombosis von; von willebrand; willebrand factor ... See more keywords
Laboratory Testing for von Willebrand Factor: Factor VIII Binding (for 2N VWD).
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7196-1_34
Abstract: Von Willebrand disease (VWD) is reportedly the most common inherited bleeding disorder and can also arise as an acquired syndrome (AVWS). These disorders develop due to defects and/or deficiency of the plasma protein von Willebrand… read more here.
Keywords: laboratory testing; von willebrand; willebrand factor; factor ... See more keywords
Clinical role of von Willebrand factor in acute ischemic stroke
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DOI: 10.1007/s00508-017-1200-4
Abstract: SummaryBackgroundAn elevated level of von Willebrand factor (VWF) is associated with an increased risk for coronary heart disease and ischemic stroke. The objective of the study was to determine whether the level of VWF is… read more here.
Keywords: ischemic stroke; acute ischemic; von willebrand; willebrand factor ... See more keywords
Successful treatment of acquired von Willebrand syndrome associated with monoclonal gammopathy
Sign Up to like & getrecommendations! Published in 2022 at "Wiener klinische Wochenschrift"
DOI: 10.1007/s00508-022-02012-3
Abstract: Acquired von Willebrand syndrome is exceedingly rare and accounts for only 1–3% of von Willebrand disease cases. In this short report, we present our own cases of acquired von Willebrand syndrome associated with monoclonal gammopathy.… read more here.
Keywords: acquired von; monoclonal gammopathy; willebrand syndrome; von willebrand ... See more keywords
Characterization of the von Willebrand factor/factor VIII complex produced by a novel purification process.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of pharmacal research"
DOI: 10.1007/s12272-020-01245-y
Abstract: Factor VIII (FVIII) is a blood coagulation protein that circulates as a complex with von Willebrand factor (vWF) in the plasma. In the survey of inhibitors in plasma product exposed toddlers (SIPPET) study, plasma-derived FVIII… read more here.
Keywords: purification; fviii; von willebrand; factor ... See more keywords