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   Articles with "vonoprazan" as a keyword



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Clinical impact of vonoprazan-based dual therapy with amoxicillin for H. pylori infection in a treatment-naïve cohort of junior high school students in Japan

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recommendations! Published in 2020 at "Journal of Gastroenterology"

DOI: 10.1007/s00535-020-01709-4

Abstract: Although 7-day triple therapy, consisting of vonoprazan, amoxicillin (AMO), and clarithromycin (CLA), is recommended for Helicobacter pylori (H. pylori) eradication in adults. However, the importance of reducing antibiotic use in pediatric patients is well recognized.… read more here.

Keywords: junior high; dual therapy; triple therapy; vonoprazan ... See more keywords
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How Does Vonoprazan Affect the Treatment of Erosive Esophagitis?

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recommendations! Published in 2020 at "Digestive Diseases and Sciences"

DOI: 10.1007/s10620-020-06387-z

Abstract: We read with great interest the recent article by Cheng et al. [1] in this journal. The authors presented a systematic review and meta-analysis of data comparing the effect of vonoprazan, a potassium-competitive acid blocker… read more here.

Keywords: vonoprazan affect; affect treatment; treatment erosive; vonoprazan ... See more keywords
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Upper gastrointestinal bleeding in Japanese patients with ischemic heart disease receiving vonoprazan or a proton pump inhibitor with multiple antithrombotic agents: A nationwide database study.

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recommendations! Published in 2020 at "Journal of cardiology"

DOI: 10.1016/j.jjcc.2020.02.012

Abstract: BACKGROUND Vonoprazan has been launched as an alternative to proton-pump inhibitors (PPIs). This was the first study to compare the occurrence of upper gastrointestinal bleeding (UGIB) with vonoprazan treatment to that with PPI treatment in… read more here.

Keywords: antithrombotic agents; upper gastrointestinal; treatment; gastrointestinal bleeding ... See more keywords
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Gastric acid inhibitor aggravates indomethacin-induced small intestinal injury via reducing Lactobacillus johnsonii

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-53559-7

Abstract: Proton pump inhibitors (PPIs) alter the composition of the intestinal microbiome, exacerbating indomethacin (IND)-induced small intestinal damage. Vonoprazan fumarate inhibits gastric acid secretion using a different mechanism from PPIs. We investigated the effects of both… read more here.

Keywords: small intestinal; induced small; ind induced; vonoprazan ... See more keywords
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VONOPRAZAN VERSUS LANSOPRAZOLE FOR HEALING AND MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS: A RANDOMIZED TRIAL.

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recommendations! Published in 2022 at "Gastroenterology"

DOI: 10.1053/j.gastro.2022.09.041

Abstract: BACKGROUND & AIMS For decades, proton pump inhibitors (PPIs) have been the mainstay of treatment for erosive esophagitis. The potassium-competitive acid blocker vonoprazan provides more potent acid inhibition than PPIs but data on its efficacy… read more here.

Keywords: erosive esophagitis; maintenance healing; vonoprazan; difference ... See more keywords
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Long-term outcomes of patients with symptomatic gastroesophageal reflux disease treated with vonoprazan

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recommendations! Published in 2018 at "Scandinavian Journal of Gastroenterology"

DOI: 10.1080/00365521.2018.1486883

Abstract: Abstract Objective: The novel potassium-competitive acid blocker, vonoprazan, provides rapid and effective acid suppression. The aim of this study is to evaluate the long-term outcomes of patients with symptomatic gastroesophageal reflux disease (GERD) treated with… read more here.

Keywords: long term; patients symptomatic; one year; gerd ... See more keywords
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Assessments of CYP‑inhibition‑based drug–drug interaction between vonoprazan and poziotinib in vitro and in vivo

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recommendations! Published in 2023 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2023.2173253

Abstract: Abstract Context Poziotinib and vonoprazan are two drugs mainly metabolized by CYP3A4. However, the drug-drug interaction between them is unknown. Objective To study the interaction mechanism and pharmacokinetics of poziotinib on vonoprazan. Materials and methods… read more here.

Keywords: poziotinib; vonoprazan; drug drug; drug interaction ... See more keywords
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A meta-analysis: the efficacy of vonoprazan for management of post-ESD ulcers compared with PPIs.

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recommendations! Published in 2019 at "Journal of digestive diseases"

DOI: 10.1111/1751-2980.12813

Abstract: OBJECTIVE As a result of resection, artificial ulcers were created after Endoscopic submucosal dissection (ESD). In order to heal the ulcers as soon as possible, vonoprazan, a novel potassium competitive acid blocker, which may have… read more here.

Keywords: esd; esd ulcers; post esd; efficacy ... See more keywords
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Vonoprazan poses no additional risk of developing Clostridioides difficile infection compared to proton pump inhibitors.

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recommendations! Published in 2023 at "Journal of gastroenterology and hepatology"

DOI: 10.1111/jgh.16169

Abstract: BACKGROUND AND AIM The use of proton pump inhibitors (PPIs) has been repeatedly reported as a trigger of Clostridioides difficile infection (CDI), a leading cause of nosocomial diarrhea. However, only a few studies have reported… read more here.

Keywords: pump inhibitors; vonoprazan; proton pump; clostridioides difficile ... See more keywords
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Effect of Vonoprazan on Delayed Bleeding after Endoscopic Submucosal Dissection for Gastric Neoplasia among Antithrombotic Drug Users: A Single-Center, Single-Arm Prospective Observational Case Control Study.

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recommendations! Published in 2020 at "Acta medica Okayama"

DOI: 10.18926/amo/59958

Abstract: Antithrombotic therapy is a major risk factor for delayed bleeding after endoscopic submucosal dissection (ESD) for gastric neoplasia. A potassium-competitive acid blocker, vonoprazan, is expected to prevent delayed bleeding better than conventional proton pomp inhibitors… read more here.

Keywords: control; vonoprazan; antithrombotic therapy; delayed bleeding ... See more keywords
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Vonoprazan Fumarate for the Treatment of Gastric Ulcers: A Short Review on Emerging Data

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recommendations! Published in 2020 at "Clinical and Experimental Gastroenterology"

DOI: 10.2147/ceg.s228352

Abstract: Abstract Potassium-competitive acid blockers (P-CABs), such as vonoprazan, represent a novel and heterogeneous class of drugs that competitively block the potassium binding site of gastric H+/K+ ATPase, thus potentially overcoming the limitations of proton-pump inhibitors.… read more here.

Keywords: review; treatment gastric; treatment; vonoprazan ... See more keywords