VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX
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DOI: 10.1186/s12915-018-0576-6
Abstract: BackgroundThe WW domain-containing oxidoreductase (WWOX) gene, frequently altered in breast cancer, encodes a tumor suppressor whose function is mediated through its interactions with cancer-related proteins, such as the pro-apoptotic protein p73α.ResultsTo better understand the involvement… read more here.
Keywords: tumor suppressor; breast tumorigenesis; vopp1; wwox ... See more keywords
MicroRNA-218 alleviates sepsis inflammation by negatively regulating VOPP1 via JAK/STAT pathway.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201809_15827
Abstract: OBJECTIVE To investigate the possible role of microRNA-218 in the pathogenesis of sepsis and its underlying mechanism. PATIENTS AND METHODS MicroRNA-218 expression in peripheral blood mononuclear cells (PBMCs) of 53 sepsis patients and 20 healthy… read more here.
Keywords: sepsis; stat pathway; jak stat; microrna 218 ... See more keywords