Adjunctive Oral Voriconazole Treatment of Fusarium Keratitis: A Secondary Analysis From the Mycotic Ulcer Treatment Trial II
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.0616
Abstract: Importance Fusarium keratitis is common and often results in poor outcomes. No new treatments since natamycin have become available. Objective To explore the role of adjuvant oral voriconazole on clinical outcomes in Fusarium keratitis. Design,… read more here.
Keywords: trial; treatment; fusarium keratitis; oral voriconazole ... See more keywords
Vision Loss Associated With the Opioid Epidemic
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.4868
Abstract: dents indicated that more evidence was needed to guide treatment choices.4 The MUTT I result was driven primarily by ulcers caused by Fusarium, which had the worst response to voriconazole.1 After the results of MUTT… read more here.
Keywords: loss associated; voriconazole; practice patterns; vision loss ... See more keywords
Predictive Value of C-Reactive Protein and Albumin for Temporal Within-Individual Pharmacokinetic Variability of Voriconazole in Pediatric Hematopoietic Cell Transplant Patients.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2024
Abstract: Voriconazole is a widely used antifungal agent in immunocompromised patients, but its utility is limited by its variable exposure and narrow therapeutic index. Population pharmacokinetic (PK) models have been used to characterize voriconazole PK and… read more here.
Keywords: voriconazole; variability; temporal within; reactive protein ... See more keywords
Voriconazole greatly increases the exposure to oral buprenorphine
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-018-2548-8
Abstract: PurposeBuprenorphine has low oral bioavailability. Regardless of sublingual administration, a notable part of buprenorphine is exposed to extensive first-pass metabolism by the cytochrome P450 (CYP) 3A4. As drug interaction studies with buprenorphine are limited, we… read more here.
Keywords: exposure oral; voriconazole; increases exposure; buprenorphine ... See more keywords
The efflux pump inhibitor tetrandrine exhibits synergism with fluconazole or voriconazole against Candida parapsilosis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-05020-1
Abstract: In the last two decades, with the wide use of azoles, antifungal resistance among Candida parapsilosis has considered a matter of concern worldwide. The aim of this study is to evaluate the antifungal potentials of… read more here.
Keywords: efflux pump; candida parapsilosis; pump inhibitor; synergism ... See more keywords
Mimicking Multiple Myeloma: Voriconazole-Induced Hyperfluorosis and Bone Lesions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of General Internal Medicine"
DOI: 10.1007/s11606-019-05551-0
Abstract: A 70-year-old man was found to have diffuse lytic and sclerotic bone lesions during a work-up to rule out malignancy after sustaining an unprovoked pulmonary embolus (Fig. 1). The patient reported several months of deep… read more here.
Keywords: bone lesions; multiple myeloma; bone; mimicking multiple ... See more keywords
Voriconazole exposure and risk of cutaneous squamous cell carcinoma among lung or hematopoietic cell transplant patients: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2018.08.010
Abstract: BACKGROUND Current evidence about the association between voriconazole and risk of cutaneous squamous cell carcinoma (SCC) remains inconsistent. OBJECTIVE To assess the association between voriconazole use and risk of SCC. METHODS We systematically searched PubMed… read more here.
Keywords: risk; cell carcinoma; voriconazole; cell ... See more keywords
Establishment and optimization of voriconazole/HS15/SBE-β-CD complex system: Based on micellization thermodynamics
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.114453
Abstract: Abstract In this paper, the interaction between different non-ionic surfactants and cyclodextrins was studied by surface tension measurement. The interface and micellization behavior of binary and ternary mixtures of Polyoxyl 15 Hydroxystearate (HS15), sulfobutylether-β-cyclodextrin (SBE-β-CD)… read more here.
Keywords: micellization; system; hs15 sbe; voriconazole ... See more keywords
Posaconazole vs. voriconazole in the prevention of invasive fungal diseases in patients with haematological malignancies: A retrospective study.
Sign Up to like & getrecommendations! Published in 2018 at "Journal de mycologie medicale"
DOI: 10.1016/j.mycmed.2017.11.003
Abstract: BACKGROUND Posaconazole is superior to fluconazole or itraconazole in preventing invasive fungal diseases (IFDs) in patients with haematological malignancies; however, there have been reports of the comparing posaconazole and voriconazole. METHODS This single-centre, retrospective study… read more here.
Keywords: fungal diseases; patients haematological; posaconazole voriconazole; invasive fungal ... See more keywords
Rapid Quantitative Detection of Voriconazole in Human Plasma Using Surface-Enhanced Raman Scattering
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04521
Abstract: There is an increasing demand for rapid detection techniques for monitoring the therapeutic concentration of voriconazole (VRC) in human biological fluids. Herein, a rapid and selective surface-enhanced Raman scatting method for point-of-care determination of VRC… read more here.
Keywords: human plasma; voriconazole; surface enhanced; detection ... See more keywords
Calcofluor white-cholesteryl hydrogen succinate conjugate mediated liposomes for enhanced targeted delivery of voriconazole into Candida albicans.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm01263d
Abstract: Fungal infections gradually lead to a high mortality rate due to difficulties in diagnosis, the limited number of antifungal drugs available, and the appearance of resistant isolates. Here, we developed a calcofluor white-cholesteryl hydrogen succinate… read more here.
Keywords: cfw chsc; voriconazole; white cholesteryl; chsc ... See more keywords