Mass spectrometric methods for evaluation of voriconazole avian pharmacokinetics and the inhibition of its cytochrome P450-induced metabolism
Sign Up to like & getrecommendations! Published in 2024 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2024.2322675
Abstract: Abstract Invasive fungal aspergillosis is a leading cause of morbidity and mortality in many species including avian species such as common ravens (Corvus corax). Methods were developed for mass spectral determination of voriconazole in raven… read more here.
Keywords: voriconazole; mass; metabolism; cytochrome p450 ... See more keywords
Effects of inflammation on voriconazole levels: A systematic review
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DOI: 10.1111/bcp.15495
Abstract: This study aimed to review the studies evaluating the effect of the inflammatory state on voriconazole (VRZ) levels. read more here.
Keywords: review; voriconazole levels; systematic review; effects inflammation ... See more keywords
The Effect of Rifapentine and Rifampicin on Serum Voriconazole Levels Persist for 5 Days and 7 Days or More After Discontinuation in Tuberculosis Patients with Chronic Pulmonary Aspergillosis
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DOI: 10.2147/idr.s461785
Abstract: Purpose Voriconazole, a first-line therapeutic agent for chronic pulmonary aspergillosis, is metabolized by the cytochrome 450 enzymes, specifically CYP2C19 and CYP3A4. Rifampicin and rifapentine act as inducers of the cytochrome P450 enzyme. The current study… read more here.
Keywords: rifampicin rifapentine; serum voriconazole; voriconazole; voriconazole levels ... See more keywords