Articles with "vorinostat conjugates" as a keyword



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Cancer-Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates.

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Published in 2022 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.2c00126

Abstract: Anticancer drug delivery by small molecules offers a number of advantages over conventional macromolecular drug delivery systems. We previously developed phenylcyclopropylamine (PCPA)-drug conjugates (PDCs) as small-molecule-based drug delivery vehicles for targeting lysine-specific demethylase 1 (LSD1)-overexpressing… read more here.

Keywords: vorinostat conjugates; vorinostat; cancer cell; drug ... See more keywords