The preclinical discovery of vosaroxin for the treatment of acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2017.1331215
Abstract: ABSTRACT Introduction: Acute myeloid leukemia (AML) represents a disease with a very poor outcome and remains an area of significant unmet need necessitating novel therapeutic strategies. Among novel therapeutic agents, vosaroxin is a first-in-class anticancer… read more here.
Keywords: discovery; myeloid leukemia; vosaroxin; acute myeloid ... See more keywords
Therapies for acute myeloid leukemia: vosaroxin
Sign Up to like & getrecommendations! Published in 2017 at "OncoTargets and therapy"
DOI: 10.2147/ott.s121477
Abstract: Vosaroxin, a quinolone-derivative chemotherapeutic agent, was considered a promising drug for the treatment of acute myeloid leukemia (AML). Early-stage clinical trials with this agent led to a large randomized double-blind placebo-controlled study of vosaroxin in… read more here.
Keywords: myeloid leukemia; vosaroxin; acute myeloid; therapies acute ... See more keywords