Crystal Structures, X-Ray Photoelectron Spectroscopy, Thermodynamic Stabilities, and Improved Solubilities of 2-Hydrochloride Salts of Vortioxetine.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2016.12.010
Abstract: Two vortioxetine (VOT) salts with hydrochloride (VOT-HCl and VOT-0.5HCl) were prepared and structurally characterized. VOT-HCl features 1-dimensional P/M helical chains through N-H···Cl hydrogen bond interactions, whereas VOT-0.5HCl possesses a 1-dimensional zigzag structure in which 2… read more here.
Keywords: vot 5hcl; vot; vot hcl; spectroscopy ... See more keywords
Vortioxetine derivatives with amino acid as promoiety: synthesis, activity, stability and preliminary pharmacokinetic study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2021.04.011
Abstract: Vortioxetine (Vot) is an effective antidepressant with unique mechanisms exerting multi-target effects. However, severe side-effects such as nausea and vomiting are commonly experienced under conditions of long-term administration. Eight amino acid modified Vot derivatives were… read more here.
Keywords: amino acid; study; vot; derivatives amino ... See more keywords
Sex differences in NIRS derived values of reactive hyperemia persist after experimentally controlling for the ischemic vasodilatory stimulus.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00174.2023
Abstract: Men and women exhibit different near-infrared spectroscopy (NIRS) outcomes in response to vascular occlusion tests (VOT), which may be due to phenotypic characteristics or different degrees of desaturation during ischemia. The minimum skeletal muscle tissue… read more here.
Keywords: vot; men women; sex; nirs derived ... See more keywords
Attentional Modulation and Individual Differences in Explaining the Changing Role of Fundamental Frequency in Korean Laryngeal Stop Perception
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DOI: 10.1177/0023830917729840
Abstract: Previous research has shown differential degrees of attention in processing hierarchical linguistic information where higher order cues require greater attention in speech processing. The current study investigated the influence of attentional resources on acoustic cue… read more here.
Keywords: korean laryngeal; laryngeal; cue; perception ... See more keywords