A Conserved Receptor-Binding Domain in the VP1u of Primate Erythroparvoviruses Determines the Marked Tropism for Erythroid Cells
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DOI: 10.3390/v14020420
Abstract: Parvovirus B19 (B19V) is a human pathogen with a marked tropism for erythroid progenitor cells (EPCs). The N-terminal of the VP1 unique region (VP1u) contains a receptor-binding domain (RBD), which mediates virus uptake through interaction… read more here.
Keywords: primate erythroparvoviruses; vp1ur; erythroid cells; vp1u ... See more keywords
Structural Dynamics and Activity of B19V VP1u during the pHs of Cell Entry and Endosomal Trafficking
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DOI: 10.3390/v14091922
Abstract: Parvovirus B19 (B19V) is a human pathogen that is the causative agent of fifth disease in children. It is also known to cause hydrops in fetuses, anemia in AIDS patients, and transient aplastic crisis in… read more here.
Keywords: cell; b19v vp1u; structural dynamics; vp1u ... See more keywords