A Conserved Receptor-Binding Domain in the VP1u of Primate Erythroparvoviruses Determines the Marked Tropism for Erythroid Cells
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DOI: 10.3390/v14020420
Abstract: Parvovirus B19 (B19V) is a human pathogen with a marked tropism for erythroid progenitor cells (EPCs). The N-terminal of the VP1 unique region (VP1u) contains a receptor-binding domain (RBD), which mediates virus uptake through interaction… read more here.
Keywords: primate erythroparvoviruses; vp1ur; erythroid cells; vp1u ... See more keywords