Chaperone-assisted selective autophagy targets filovirus VP40 as a client and restricts egress of virus particles.
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DOI: 10.1073/pnas.2210690120
Abstract: The filovirus VP40 protein directs virion egress, which is regulated either positively or negatively by select VP40-host interactions. We demonstrate that host BAG3 and HSP70 recognize VP40 as a client and inhibit the egress of… read more here.
Keywords: chaperone assisted; assisted selective; vp40 client; filovirus vp40 ... See more keywords