Intradermal and intranasal immunizations with oligomeric middle layer rotavirus VP6 induce Th1, Th2 and Th17 T cell subsets and CD4+ T lymphocytes with cytotoxic potential
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2018.06.012
Abstract: ABSTRACT Rotavirus (RV) inner capsid VP6 protein is a potential non‐live vaccine candidate due to high degree of conservation and immunogenicity, and ability to self‐assemble into oligomeric structures, including nanotubes. These VP6 structures induce strong… read more here.
Keywords: vp6; cd4 cells; intradermal intranasal; vp6 specific ... See more keywords
Lactobacillus casei Ghosts as a Vehicle for the Delivery of DNA Vaccines Mediate Immune Responses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.849409
Abstract: We developed Lactobacillus casei bacterial ghosts (BGs) as vehicles for delivering DNA vaccines and analyzed their effects on immune responses. Uptake of the plasmids encoding the enhanced green fluorescent protein (pCI-EGFP) and BGs loaded with… read more here.
Keywords: vp6; bgs loaded; bgs; porv vp6 ... See more keywords
Rotavirus VP6 as an Adjuvant for Bivalent Norovirus Vaccine Produced in Nicotiana benthamiana
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11050229
Abstract: Rotaviruses (RVs) and noroviruses (NoVs) are major causes of childhood acute gastroenteritis. During development of a combination vaccine based on NoV virus-like particles (VLP) and RV VP6 produced in baculovirus expression system in insect cells,… read more here.
Keywords: bivalent; vp6; vp6 adjuvant; nov vlps ... See more keywords