Overexpression of the VRK1 kinase, which is associated with breast cancer, induces a mesenchymal to epithelial transition in mammary epithelial cells
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DOI: 10.1371/journal.pone.0203397
Abstract: Vaccinia-related kinase 1 (VRK1) is a pro-proliferative nuclear kinase. Mice engrafted with VRK1-depleted MDA-MB-231 breast cancer cells have been shown to develop fewer distal metastases than controls, suggesting VRK1 might play a role in cell… read more here.
Keywords: overexpression; vrk1; vrk1 overexpression; breast cancer ... See more keywords