Articles with "vrn101099" as a keyword



Abstract LB284: VRN101099: A novel treatment option for HER2-driven cancer patients, overcoming T-DXd resistance and brain metastases

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-lb284

Abstract: Many systemic therapeutic options for advanced metastatic HER2-positive breast cancer have been approved, including antibody-based therapies, chemotherapies, and tyrosine kinase inhibitors (TKIs). However, brain metastasis and acquired resistance are still major unmet medical needs for… read more here.

Keywords: vrn101099; cancer; resistance; brain ... See more keywords