Sequential disruption of SPLASH-identified vRNA-vRNA interactions challenges their role in influenza A virus genome packaging.
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DOI: 10.1093/nar/gkad442
Abstract: A fundamental step in the influenza A virus (IAV) replication cycle is the coordinated packaging of eight distinct genomic RNA segments (i.e. vRNAs) into a viral particle. Although this process is thought to be controlled… read more here.
Keywords: genome packaging; vrna vrna; vrna interactions; influenza virus ... See more keywords