Association of Retinoic Acid Receptor &bgr; Gene With Onset and Progression of Lichen Sclerosus–Associated Vulvar Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.1373
Abstract: Importance Molecular alterations in lichen sclerosus–associated vulvar squamous cell carcinoma (LS-VSCC) are largely unknown. Objective To determine whether the retinoic acid receptor &bgr; (RAR&bgr;) tumor-suppressor gene is involved in the onset and/or progression of LS-VSCC.… read more here.
Keywords: bgr; rar bgr; vscc; normal skin ... See more keywords
Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets.
Sign Up to like & getrecommendations! Published in 2018 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.06.026
Abstract: BACKGROUND Vulvar squamous cell carcinoma (VSCC) constitutes over 90% of vulvar cancer. Its pathogenesis can follow two different pathways; high risk human papillomavirus (hrHPV)-dependent and HPV-independent. Due to the rarity of VSCC, molecular mechanisms underlying… read more here.
Keywords: hrhpv hrhpv; somatic mutation; vscc; hrhpv ... See more keywords
Potential targets for tumor-specific imaging of vulvar squamous cell carcinoma: A systematic review of candidate biomarkers.
Sign Up to like & getrecommendations! Published in 2020 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2019.12.030
Abstract: INTRODUCTION Vulvar squamous cell carcinoma (VSCC) is a rare malignancy with an increasing incidence, especially in young women. Surgical treatment of VSCC is associated with significant morbidity and high recurrence rates, which is related to… read more here.
Keywords: vscc; tumor specific; vulvar squamous; specific imaging ... See more keywords
Human papillomavirus and p53 status define three types of vulvar squamous cell carcinomas with distinct clinical, pathological, and prognostic features.
Sign Up to like & getrecommendations! Published in 2023 at "Histopathology"
DOI: 10.1111/his.14925
Abstract: INTRODUCTION Based on their etiological relationship with human papillomavirus (HPV), the 2020 WHO classification has divided vulvar squamous cell carcinomas (VSCC) into two distinct types, HPV-associated and HPV-independent, and HPV-independent tumours have recently been divided… read more here.
Keywords: vscc; hpv independent; p53 status; p53 ... See more keywords
Inflammatory Proteins HMGA2 and PRTN3 as Drivers of Vulvar Squamous Cell Carcinoma Progression
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers13010027
Abstract: Simple Summary Our study aimed to advance the understanding of vulvar squamous cell carcinoma (VSCC) biology by recognizing biological pathways that drive the progression of this disease. We applied the experimental path from global proteomic… read more here.
Keywords: carcinoma; squamous cell; vscc; biology ... See more keywords