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Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.1373
Abstract: Importance Molecular alterations in lichen sclerosus–associated vulvar squamous cell carcinoma (LS-VSCC) are largely unknown. Objective To determine whether the retinoic acid receptor &bgr; (RAR&bgr;) tumor-suppressor gene is involved in the onset and/or progression of LS-VSCC.…
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Keywords:
bgr;
rar bgr;
vscc;
normal skin ... See more keywords
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Published in 2018 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.06.026
Abstract: BACKGROUND Vulvar squamous cell carcinoma (VSCC) constitutes over 90% of vulvar cancer. Its pathogenesis can follow two different pathways; high risk human papillomavirus (hrHPV)-dependent and HPV-independent. Due to the rarity of VSCC, molecular mechanisms underlying…
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Keywords:
hrhpv hrhpv;
somatic mutation;
vscc;
hrhpv ... See more keywords
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Published in 2020 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2019.12.030
Abstract: INTRODUCTION Vulvar squamous cell carcinoma (VSCC) is a rare malignancy with an increasing incidence, especially in young women. Surgical treatment of VSCC is associated with significant morbidity and high recurrence rates, which is related to…
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Keywords:
vscc;
tumor specific;
vulvar squamous;
specific imaging ... See more keywords
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Published in 2023 at "Histopathology"
DOI: 10.1111/his.14925
Abstract: INTRODUCTION Based on their etiological relationship with human papillomavirus (HPV), the 2020 WHO classification has divided vulvar squamous cell carcinomas (VSCC) into two distinct types, HPV-associated and HPV-independent, and HPV-independent tumours have recently been divided…
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Keywords:
vscc;
hpv independent;
p53 status;
p53 ... See more keywords
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Published in 2020 at "Cancers"
DOI: 10.3390/cancers13010027
Abstract: Simple Summary Our study aimed to advance the understanding of vulvar squamous cell carcinoma (VSCC) biology by recognizing biological pathways that drive the progression of this disease. We applied the experimental path from global proteomic…
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Keywords:
carcinoma;
squamous cell;
vscc;
biology ... See more keywords