Articles with "vsg" as a keyword



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Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.

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Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109923

Abstract: The dense variant surface glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing of the pathogen by employing a large repertoire of antigenically distinct VSG genes, thus neutralizing the… read more here.

Keywords: nanobody mediated; mediated macromolecular; vsg; nanobody ... See more keywords

A Self-Regulated Virtual Impedance control of VSG in a microgrid

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Published in 2021 at "Electric Power Systems Research"

DOI: 10.1016/j.epsr.2021.107289

Abstract: Abstract In this paper, a self-regulated virtual impedance (SRVI) control of virtual synchronous generator (VSG) is proposed. In the modern power system, large penetration of inverter-interfaced distributed generator (DG) decreases the equivalent inertia of the… read more here.

Keywords: vsg; regulated virtual; control; self regulated ... See more keywords

Temperature shift activates bloodstream VSG expression site promoters in Trypanosoma brucei.

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Published in 2018 at "Molecular and biochemical parasitology"

DOI: 10.1016/j.molbiopara.2018.10.003

Abstract: Trypanosoma brucei relies on two types of variant surface glycoprotein (VSG) expression sites (ESs) for RNA polymerase I (Pol I) transcription of VSG pre-mRNA. Trypanosomes developing into infectious metacyclic cells in the tsetse vector use… read more here.

Keywords: bloodstream vsg; vsg; temperature; vsg expression ... See more keywords

Vertical sleeve gastrectomy increases duodenal Lactobacillus spp. richness associated with the activation of intestinal HIF2α signaling and metabolic benefits

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Published in 2022 at "Molecular Metabolism"

DOI: 10.1016/j.molmet.2022.101432

Abstract: Objective Vertical Sleeve Gastrectomy (VSG) is one of the most efficacious treatments for obesity and its comorbidities. Although a range of evidence suggests that alterations of the microbiota in the distal gut following VSG are… read more here.

Keywords: vsg; lactobacillus spp; duodenum; physiology ... See more keywords

Identification of potential protein partners that bind to the variant surface glycoprotein in Trypanosoma equiperdum

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Published in 2017 at "Parasitology"

DOI: 10.1017/s003118201700004x

Abstract: SUMMARY Trypanosoma equiperdum possesses a dense coat of a variant surface glycoprotein (VSG) that is used to evade the host immune response by a process known as antigenic variation. Soluble and membrane forms of the… read more here.

Keywords: protein; vsg; trypanosoma equiperdum; surface ... See more keywords
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Variant antigen diversity in Trypanosoma vivax is not driven by recombination

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Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-14575-8

Abstract: African trypanosomes (Trypanosoma) are vector-borne haemoparasites that survive in the vertebrate bloodstream through antigenic variation of their Variant Surface Glycoprotein (VSG). Recombination, or rather segmented gene conversion, is fundamental in Trypanosoma brucei for both VSG… read more here.

Keywords: trypanosoma vivax; recombination; vsg; diversity ... See more keywords

Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat

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Published in 2017 at "Nature Microbiology"

DOI: 10.1038/s41564-017-0013-6

Abstract: The most prominent defence of the unicellular parasite Trypanosoma brucei against the host immune system is a dense coat that comprises a variant surface glycoprotein (VSG). Despite the importance of the VSG family, no complete… read more here.

Keywords: vsg; surface glycoprotein; surface; variant surface ... See more keywords

Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei

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Published in 2024 at "Nature"

DOI: 10.1038/s41586-024-08151-z

Abstract: The protozoan parasite Trypanosoma brucei evades clearance by the host immune system through antigenic variation of its dense variant surface glycoprotein (VSG) coat, periodically ‘switching’ expression of the VSG using a large genomic repertoire of… read more here.

Keywords: vsg; trypanosoma brucei; antigenic diversity; extravascular spaces ... See more keywords
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Vertical sleeve gastrectomy induces distinctive transcriptomic responses in liver, fat and muscle

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-81866-5

Abstract: Vertical sleeve gastrectomy (VSG) is the most commonly performed bariatric/metabolic surgery, exhibiting a high rate of diabetes remission in humans. To elucidate the molecular mechanisms of VSG, we performed transcriptomic analysis of the liver, fat,… read more here.

Keywords: vsg; fat muscle; group; liver fat ... See more keywords

Effects analysis of excitation circuit on power control for VSG: a design‐oriented study

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Published in 2019 at "Iet Renewable Power Generation"

DOI: 10.1049/iet-rpg.2019.0389

Abstract: Reactive power control loop (RPCL) in virtual synchronous generator (VSG) plays the role of excitation circuit in conventional SG. The control strategy improvement or parameters configuration method of RPCL is always the emphasis of analysis.… read more here.

Keywords: vsg; control; power; excitation circuit ... See more keywords

A modified synchronverter for a weak grid with virtual power circles‐based PQ decoupling scheme

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Published in 2024 at "IET Renewable Power Generation"

DOI: 10.1049/rpg2.13118

Abstract: The high penetration of renewable energy sources (RES) results in a low‐inertia, weak power grid. To mitigate this and restore system inertia, it has been widely proposed to operate the inverters of RES units to… read more here.

Keywords: modified synchronverter; scheme; vsg; grid ... See more keywords