Variant antigen repertoires in Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data using universal protein motifs.
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DOI: 10.1101/gr.234146.118
Abstract: African trypanosomes are vector-borne hemoparasites of humans and animals. In the mammal, parasites evade the immune response through antigenic variation. Periodic switching of the variant surface glycoprotein (VSG) coat covering their cell surface allows sequential… read more here.
Keywords: vsg diversity; sequence; variant antigen; trypanosoma congolense ... See more keywords