BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate
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DOI: 10.3390/ijms22179263
Abstract: Vascular calcification associated with high plasma phosphate (Pi) level is a frequent complication of hyperglycemia, diabetes mellitus, and chronic kidney disease. BGP-15 is an emerging anti-diabetic drug candidate. This study was aimed to explore whether… read more here.
Keywords: vsmc calcification; bgp; calcification; inhibits hyperglycemia ... See more keywords
Exosomal STAT1 derived from high phosphorus-stimulated vascular endothelial cells induces vascular smooth muscle cell calcification via the Wnt/β-catenin signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2022.5195
Abstract: Vascular calcification is commonly observed in chronic kidney disease. The mechanism of how the calcification signal from endothelial cells is transmitted to vascular smooth muscle cells (VSMCs) remains unknown. The aim of the present study… read more here.
Keywords: vsmc calcification; calcification; signaling pathway; wnt catenin ... See more keywords