Circ‐Sirt1 inhibits vascular smooth muscle cells proliferation via the c‐Myc/cyclin B1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11758
Abstract: Vascular smooth muscle cells (VSMCs) are an important cellular component of the vascular wall. Restenosis is mainly due to VSMC excessive proliferation. However, little is known about the role of circRNAs in VSMC proliferation and… read more here.
Keywords: myc; vsmcs; circ sirt1; proliferation ... See more keywords
Different effects of neuropeptide Y on proliferation of vascular smooth muscle cells via regulation of Geminin
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3028-7
Abstract: The proliferation-promoting effect of neuropeptide Y (NPY) always functions in low-serum-cultured vascular smooth muscle cells (VSMCs), and the phenotypic switch of VSMCs is regulated by concentrations of serum. Whether the property of the NPY proliferative… read more here.
Keywords: vsmcs; vascular smooth; proliferation; muscle cells ... See more keywords
Endothelial regulation of calmodulin expression and eNOS-calmodulin interaction in vascular smooth muscle.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-022-04391-7
Abstract: Calmodulin (CaM) is a Ca2+ sensor protein that is required for numerous vascular smooth muscle cell (VSMC) functions. Since CaM is not expressed enough for its many target proteins, factors that modulate its expression and… read more here.
Keywords: cam; ecs; expression; vascular smooth ... See more keywords
Urantide alleviates the symptoms of atherosclerotic rats in vivo and in vitro models through the JAK2/STAT3 signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174037
Abstract: Atherosclerosis is the leading cause of human death, and its occurrence and development are related to the urotensin II (UII) and UII receptor (UT) system and the biological function of vascular smooth muscle cells (VSMCs).… read more here.
Keywords: jak2 stat3; vsmcs; signaling pathway; atherosclerotic rats ... See more keywords
SQSTM1/p62 deficiency induces oxidative stress and senescence in vivo and in vitro in VSMCs
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.312
Abstract: Aging is a major contributor to age-related diseases including cardiovascular disease (CVD). Vascular senescence, a hallmark of mammalian aging, has been linked to vascular disease like atherosclerosis. We previously showed that the NADPH oxidase Nox1… read more here.
Keywords: vsmcs; senescence; p62; induces oxidative ... See more keywords
miR-125a-5p Modulates Phenotypic Switch of Vascular Smooth Muscle Cells by Targeting ETS-1.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2017.05.008
Abstract: MicroRNAs are key regulators of vascular smooth muscle cells (VSMCs) phenotypic switch, one of the main events responsible for bare metal in-stent restenosis after percutaneous coronary intervention. miR-125a-5p is an important modulator of differentiation, proliferation,… read more here.
Keywords: vsmcs; vascular smooth; smooth muscle; mir 125a ... See more keywords
Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2019.04.020
Abstract: &NA; Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, in the medial layer of the arteries. AMC shares some similarities to skeletal mineralisation and has been associated with the… read more here.
Keywords: vsmcs; vascular smooth; calcifying vsmcs; calcification ... See more keywords
Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular and Cellular Cardiology"
DOI: 10.1016/j.yjmcc.2017.12.007
Abstract: Aims Calcium phosphate (CaP) particle deposits are found in several inflammatory diseases including atherosclerosis and osteoarthritis. CaP, and other forms of crystals and particles, can promote inflammasome formation in macrophages leading to caspase-1 activation and… read more here.
Keywords: caspase; vsmcs; cap particles; activation ... See more keywords
MicroRNA-146b-3p regulates the dysfunction of vascular smooth muscle cells via repressing phosphoinositide-3 kinase catalytic subunit gamma.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1937904
Abstract: MicroRNAs are crucial regulators in the phenotype switch of vascular smooth muscle cells (VSMCs). Nonetheless, the role of miR-146b-3p in VSMCs remains unclear. In the present study, platelet-derived growth factor-BB (PDGF-BB) at different concentrations was… read more here.
Keywords: pik3cg; vsmcs; vascular smooth; muscle cells ... See more keywords
Membrane cholesterol and substrate stiffness co-ordinate to induce the remodelling of the cytoskeleton and the alteration in the biomechanics of vascular smooth muscle cells.
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular research"
DOI: 10.1093/cvr/cvy276
Abstract: AIMS Cholesterol not only deposits in foam cells at the atherosclerotic plaque, but also plays an important role as a regulator of cell migration in atherogenesis. In addition, the progression of atherosclerosis leads to arterial… read more here.
Keywords: stiffness; biomechanics; vsmcs; cholesterol ... See more keywords
Transduction Efficiency of Adenovirus Vectors in Endothelial Cells and Vascular Smooth Muscle Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000821
Abstract: Adenoviral vectors are useful tools to manipulate a gene of interest in vitro and in vivo, including in the vascular system. The transduction efficiencies of adenoviral vectors in vascular cells such as endothelial cells (ECs)… read more here.
Keywords: efficiency; adenovirus; vsmcs; transduction efficiency ... See more keywords