Projection-Target-Defined Effects of Orexin and Dynorphin on VTA Dopamine Neurons.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.01.030
Abstract: Circuit-specific signaling of ventral tegmental area (VTA) dopamine neurons drives different aspects of motivated behavior, but the neuromodulatory control of these circuits is unclear. We tested the actions of co-expressed lateral hypothalamic peptides, orexin A… read more here.
Keywords: projection target; dopamine neurons; vta dopamine;
Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.1101/2023.06.13.544720
Abstract: Dopamine and orexins (hypocretins) play important roles in regulating reward-seeking behaviors. It is known that hypothalamic orexinergic neurons project to dopamine neurons in the ventral tegmental area (VTA), where they can stimulate dopaminergic neuronal activity.… read more here.
Keywords: stimulation vta; dopamine; vta dopamine; neuronal activity ... See more keywords
Neuropeptide-Y alters VTA dopamine neuron activity through both pre- and postsynaptic mechanisms.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of neurophysiology"
DOI: 10.1152/jn.00879.2016
Abstract: The mesocorticolimbic dopamine system, the brain's reward system, regulates many different behaviors including food intake, food reward, and feeding-related behaviors, and there is increasing evidence that hypothalamic feeding-related neuropeptides alter dopamine neuron activity to affect… read more here.
Keywords: neuron activity; activity; dopamine neuron; dopamine neurons ... See more keywords
The Formation and Function of the VTA Dopamine System
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25073875
Abstract: The midbrain dopamine system is a sophisticated hub that integrates diverse inputs to control multiple physiological functions, including locomotion, motivation, cognition, reward, as well as maternal and reproductive behaviors. Dopamine is a neurotransmitter that binds… read more here.
Keywords: vta dopamine; dopamine system; dopamine; formation function ... See more keywords