Leptin attenuates D2 receptor‐mediated inhibition of putative ventral tegmental area dopaminergic neurons
Sign Up to like & getrecommendations! Published in 2018 at "Physiological Reports"
DOI: 10.14814/phy2.13631
Abstract: Obesity causes hyperleptinemia. We have previously shown that D2 receptor‐mediated inhibition of ventral tegmental area (VTA) dopaminergic neurons is attenuated in diet‐induced mice with obesity. Consequently, we hypothesized that high concentrations of serum leptin during… read more here.
Keywords: leptin; vta dopaminergic; mediated inhibition; dopaminergic neurons ... See more keywords
The VTA dopaminergic system as diagnostic and therapeutical target for Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.1039725
Abstract: Neuropsychiatric symptoms (NPS) occur in nearly all patients with Alzheimer's Disease (AD). Most frequently they appear since the mild cognitive impairment (MCI) stage preceding clinical AD, and have a prognostic importance. Unfortunately, these symptoms also… read more here.
Keywords: vta; dopaminergic system; disease; alzheimer disease ... See more keywords