AKT1 and genetic vulnerability to bipolar disorder
Sign Up to like & getrecommendations! Published in 2020 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2019.112677
Abstract: AKT1 encodes a serine/threonine kinase that has as one of its best-known substrates glycogen synthase kinase-3 (GSK3), a primary target for lithium. AKT1 has been previously been implicated as a vulnerability gene for bipolar disorder… read more here.
Keywords: akt1 genetic; vulnerability; vulnerability bipolar; bipolar disorder ... See more keywords
Vulnerability to bipolar disorder is linked to sleep and sleepiness
Sign Up to like & getrecommendations! Published in 2019 at "Translational Psychiatry"
DOI: 10.1038/s41398-019-0632-1
Abstract: Sleep impairments are a hallmark of acute bipolar disorder (BD) episodes and are present even in the euthymic state. Studying healthy subjects who are vulnerable to BD can improve our understanding of whether sleep impairment… read more here.
Keywords: disorder linked; disorder; sleepiness; vulnerability bipolar ... See more keywords