Selective vulnerability of inhibitory networks in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neuropathologica"
DOI: 10.1007/s00401-020-02258-z
Abstract: In multiple sclerosis (MS), a chronic demyelinating disease of the central nervous system, neurodegeneration is detected early in the disease course and is associated with the long-term disability of patients. Neurodegeneration is linked to both… read more here.
Keywords: vulnerability inhibitory; multiple sclerosis; neurodegeneration; selective vulnerability ... See more keywords
Delineating selective vulnerability of inhibitory interneurons in Alpers' syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12833
Abstract: Alpers' syndrome is a severe neurodegenerative disease typically caused by bi‐allelic variants in the mitochondrial DNA (mtDNA) polymerase gene, POLG, leading to mtDNA depletion. Intractable epilepsy, often with an occipital focus, and extensive neurodegeneration are… read more here.
Keywords: delineating selective; vulnerability inhibitory; inhibitory; alpers syndrome ... See more keywords