Abstract PR16: A druggable transcriptional vulnerability in NRF2-dependent lung cancer
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DOI: 10.1158/1538-8514.synthleth-pr16
Abstract: The b-ZIP transcription factor NRF2 is a master regulator of the cellular antioxidant response and frequently activated in Non-Small Cell Lung Cancers (NSCLCs). While direct pharmacological inhibition of NRF2 has proven challenging, its aberrant activation… read more here.
Keywords: vulnerability nrf2; nrf2 dependent; druggable transcriptional; lung ... See more keywords