Articles with "vulnerable plaque" as a keyword



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Current research and future prospects of IVOCT imaging‐based detection of the vascular lumen and vulnerable plaque

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Published in 2022 at "Journal of Biophotonics"

DOI: 10.1002/jbio.202100376

Abstract: Intravascular optical coherence tomography (IVOCT) is an imaging method that has developed rapidly in recent years and is useful in coronary atherosclerosis diagnosis. It is widely used in the assessment of vulnerable plaque. This review… read more here.

Keywords: current research; research future; vulnerable plaque; ivoct imaging ... See more keywords
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Carotid vulnerable plaque coexisting with cerebral small vessel disease and acute ischemic stroke: a Chinese Atherosclerosis Risk Evaluation study

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Published in 2022 at "European Radiology"

DOI: 10.1007/s00330-022-08757-9

Abstract: We aimed to investigate the associations between carotid vulnerable plaque features coexisting with cerebral small vessel diseases (CSVDs) and acute ischemic stroke (AIS) and, furthermore, to determine whether coexisting diseases had a stronger association with… read more here.

Keywords: acute ischemic; vulnerable plaque; ischemic stroke; carotid vulnerable ... See more keywords
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Evaluation and Management of the Vulnerable Plaque

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Published in 2019 at "Current Cardiovascular Risk Reports"

DOI: 10.1007/s12170-019-0606-0

Abstract: Purpose of ReviewCoronary plaque rupture is the dominant mechanism of acute myocardial infarction and sudden coronary death. If we are to make a major inroads on reducing morbidity and mortality from cardiovascular disease, more accurate… read more here.

Keywords: vulnerable plaque; plaque concept; disease; cardiovascular risk ... See more keywords
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Role of new imaging modalities in pursuit of the vulnerable plaque and the vulnerable patient.

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Published in 2018 at "International journal of cardiology"

DOI: 10.1016/j.ijcard.2017.10.046

Abstract: Numerous biomarkers and imaging modalities were investigated during the past few decades to identify patients harboring plaques at high risk of rupturing and causing catastrophic events. The classical description of a vulnerable plaque included a… read more here.

Keywords: vulnerable patient; vulnerable plaque; new imaging; role new ... See more keywords
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The changing landscape of the vulnerable plaque: A call for fine-tuning of preclinical models.

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Published in 2021 at "Vascular pharmacology"

DOI: 10.1016/j.vph.2021.106924

Abstract: For decades, the pathological definition of the vulnerable plaque led to invaluable insights into the mechanisms that underlie myocardial infarction and stroke. Beyond plaque rupture, other mechanisms, such as erosion, may elicit thrombotic events underlining… read more here.

Keywords: plaque call; vulnerable plaque; landscape vulnerable; call fine ... See more keywords
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Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients.

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Published in 2019 at "Journal of molecular and cellular cardiology"

DOI: 10.1016/j.yjmcc.2019.01.002

Abstract: AIMS Mouse studies have established distinct monocyte subtypes that participate in the process of atherosclerotic lesion formation. The pro-inflammatory Ly6Chigh monocyte subtype actively contributes to murine plaque progression and destabilization. Also in humans, different peripheral… read more here.

Keywords: vulnerable plaque; cd16 classical; monocytes associate; cd14 cd16 ... See more keywords
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Analysis of Predictive Model of Coronary Vulnerable Plaque under Hemodynamic Numerical Simulation

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Published in 2022 at "Journal of Healthcare Engineering"

DOI: 10.1155/2022/3434910

Abstract: Objective Vulnerable plaque is considered to be the cause of most clinical coronary arteries, and linear cytokines are an important factor causing plaque instability. Early prediction of vulnerable plaque is of great significance in the… read more here.

Keywords: predictive model; model coronary; plaque; vulnerable plaque ... See more keywords
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Multitarget Vulnerable Plaque Imaging.

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Published in 2017 at "Circulation. Cardiovascular imaging"

DOI: 10.1161/circimaging.117.006491

Abstract: The search for the vulnerable plaque has been a prolonged, circuitous journey that despite considerable investment and resource expenditure has hitherto failed to alter clinical practice. The rationale remains enticing. We have known for some… read more here.

Keywords: vulnerable plaque; virtual histology; intravascular ultrasound; histology intravascular ... See more keywords
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m6A RNA Methylation Decreases Atherosclerotic Vulnerable Plaque Through Inducing T Cells

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Published in 2022 at "Brazilian Journal of Cardiovascular Surgery"

DOI: 10.21470/1678-9741-2021-0039

Abstract: Introduction Knockdown of fat mass and obesity-associated gene (FTO) can induce N6-methyladenosine (m6A) ribonucleic acid (RNA) methylation. The objective of this study was to explore the effect of m6A RNA methylation on atherosclerotic vulnerable plaque… read more here.

Keywords: vulnerable plaque; group; rna methylation; m6a rna ... See more keywords
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Statins and vulnerable plaque.

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Published in 2017 at "Current pharmaceutical design"

DOI: 10.2174/1381612823666171019161609

Abstract: BACKGROUND Atherosclerosis is a systemic, progressive lipid-driven inflammatory disease of the arterial vascular wall leading progressively to plaque development. The vulnerable plaque, the one considered to be the leading cause of cardiovascular events seems to… read more here.

Keywords: plaque; vulnerable plaque; statins vulnerable;
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Current Toolset in Predicting Acute Coronary Thrombotic Events: The “Vulnerable Plaque” in a “Vulnerable Patient” Concept

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Published in 2023 at "Life"

DOI: 10.3390/life13030696

Abstract: Despite major advances in pharmacotherapy and interventional procedures, coronary artery disease (CAD) remains a principal cause of morbidity and mortality worldwide. Invasive coronary imaging along with the computation of hemodynamic forces, primarily endothelial shear stress… read more here.

Keywords: acute coronary; plaque; vulnerable plaque; concept ... See more keywords