Multiphoton microscopy assessment of the structure and variability changes of dermal connective tissue in vulvar lichen sclerosus: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200036
Abstract: In this article, we offer a novel classification of progressive changes in the connective tissue of dermis in vulvar lichen sclerosus (VLS) relying on quantitative assessment of the second harmonic generation (SHG) signal received from… read more here.
Keywords: microscopy; vulvar lichen; connective tissue; lichen sclerosus ... See more keywords
The long-term clinical consequences of Juvenile Vulvar Lichen Sclerosus, a systematic review.
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DOI: 10.1016/j.jaad.2019.08.030
Abstract: BACKGROUND Vulvar lichen sclerosus (VLS) occurring in juveniles (children and adolescents) may have repercussions throughout life. OBJECTIVE We sought to assess the evidence available on the long-term consequences of juvenile vulvar lichen sclerosus (JVLS). METHODS… read more here.
Keywords: lichen sclerosus; long term; vulvar lichen; term ... See more keywords
Comparison of efficacy and safety of high-intensity focused ultrasound at different powers for patients with vulvar lichen simplex chronicus
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DOI: 10.1080/02656736.2021.1926561
Abstract: Abstract Objective To compare the efficacy and safety of the treatment of vulvar lichen simplex chronicus (VLSC) using high-intensity focused ultrasound (HIFU) at different powers. Methods This retrospective study included 152 patients with VLSC. Among… read more here.
Keywords: efficacy safety; vulvar lichen; simplex chronicus; treatment ... See more keywords
Combined therapy in vulvar lichen sclerosus: does topical tretinoin improve the efficacy of mometasone furoate?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2016.1277178
Abstract: Abstrract Purpose: To assess efficacy and safety profile of combining a potent corticosteroid with a retinoid in the treatment of vulvar lichen sclerosus (VLS). Methods: We retrospectively compared 21 VLS patients treated with tretinoin (T)… read more here.
Keywords: vulvar lichen; group; mometasone furoate; efficacy ... See more keywords
Treatment-induced anogenital melanosis is a very frequent finding in patients with vulvar lichen sclerosus
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Women's Dermatology"
DOI: 10.1097/jw9.0000000000000169
Abstract: Background: Pigmented lesions such as melanosis have rarely been reported in patients with vulvar lichen sclerosus (VLS) that is typically characterized by hypopigmented lesions. Objective: We aimed to analyze systematically anogenital melanosis in a large… read more here.
Keywords: treatment; melanosis; vulvar lichen; patients vulvar ... See more keywords
Comorbid Vulvar Lichen Planus and Lichen Sclerosus
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DOI: 10.1097/lgt.0000000000000307
Abstract: Objectives The aims of the study are to assess the histopathologic characteristics of vulvar biopsies consistent with lichen planus (LP) in women with a previous or concurrent histopathologic diagnosis of vulvar lichen sclerosus (LS) and… read more here.
Keywords: vulvar lichen; lichen; histopathology; comorbid vulvar ... See more keywords
Development of the Adult Vulvar Lichen Sclerosus Severity Scale—A Delphi Consensus Exercise for Item Generation
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DOI: 10.1097/lgt.0000000000000361
Abstract: Objective To generate a list of items through international expert consensus consisting of both symptoms and clinical signs for inclusion in an adult vulvar lichen sclerosus severity scale. Methods This study was carried out as… read more here.
Keywords: vulvar lichen; adult vulvar; sclerosus severity; consensus ... See more keywords
Genomic Profiling of Vulvar Lichen Sclerosus Patients Shows Possible Pathogenetic Disease Mechanisms.
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DOI: 10.1097/lgt.0000000000000482
Abstract: OBJECTIVE Vulvar lichen sclerosus (LS) is known to occur in families, suggesting a genetic link. Genomic profiling of patients with vulvar LS was investigated to find underlying pathogenetic mechanisms, with the hope that targeted therapies… read more here.
Keywords: genomic profiling; lichen sclerosus; vulvar lichen; family ... See more keywords
Presenting Symptoms and Diagnosis of Vulvar Lichen Sclerosus in Premenopausal Women: A Cross-Sectional Study.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of lower genital tract disease"
DOI: 10.1097/lgt.0000000000000679
Abstract: OBJECTIVES/PURPOSE Presenting symptoms of vulvar lichen sclerosus (LS) specific to premenopausal women are not well reported in the literature and may differ from those in postmenopausal women. This study aimed to characterize the presentation of… read more here.
Keywords: diagnosis; vulvar lichen; presenting symptoms; premenopausal women ... See more keywords
Outcome Measures in Adult Vulvar Lichen Sclerosus: A Systematic Review
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DOI: 10.1097/lgt.0000000000000819
Abstract: Objectives Core outcome domains (CODs) for treatment of adult vulvar lichen sclerosus (VLS) have recently been established through a Delphi study. A number of measuring tools are available for evaluating VLS. The aim of this… read more here.
Keywords: vls; lichen sclerosus; vulvar lichen; outcome ... See more keywords
The Barriers and Perceived Benefits to Vulvar Self-Examination in the Management of Vulvar Lichen Sclerosus
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DOI: 10.1097/lgt.0000000000000848
Abstract: Objectives It is common practice to advise people with vulvar lichen sclerosus to perform vulvar self-examination (VSE) to optimize topical therapy and detect changes that may represent active disease, scarring, and/or squamous cell carcinoma development.… read more here.
Keywords: vulvar self; vse; lichen sclerosus; vulvar lichen ... See more keywords