Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells
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DOI: 10.1161/circulationaha.117.032273
Abstract: Background: The progression toward low-cost and rapid next-generation sequencing has uncovered a multitude of variants of uncertain significance (VUS) in both patients and asymptomatic “healthy” individuals. A VUS is a rare or novel variant for… read more here.
Keywords: vusmyl3 170c; uncertain significance; pathogenicity; genomic variant ... See more keywords