Profile of von Willebrand factor antigen and von Willebrand factor propeptide in an overall TIA and ischaemic stroke population and amongst subtypes
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DOI: 10.1016/j.jns.2017.02.045
Abstract: INTRODUCTION Von Willebrand factor propeptide (VWF:Ag II) is proposed to be a more sensitive marker of acute endothelial activation than von Willebrand factor antigen (VWF:Ag). Simultaneous data on VWF:Ag and VWF:Ag II profiles are very… read more here.
Keywords: vwf levels; vwf; von willebrand; willebrand factor ... See more keywords
Bleeding Patterns in Type I VWD in Effect of VWF Levels: An Individual Participant Data Meta-Analysis of Three Cohorts
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DOI: 10.1182/blood-2018-99-115728
Abstract: Type I von Willebrand disease (VWD) is the most frequent bleeding disorder, with a prevalence of 10-50 cases per 10,000 persons. VWD usually shows an autosomal dominant inheritance pattern, at least in families having VWF:Ag… read more here.
Keywords: type vwd; vwf levels; vwf; bleeding ... See more keywords
Epigenetic Profiles of Primary Endothelial Cells from Patients with Low VWF Levels
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DOI: 10.1182/blood-2018-99-116719
Abstract: Background Von Willebrand disease (VWD) type 1 is characterized by low von Willebrand factor (VWF) levels and mucocutaneous bleeding (MCB). Approximately 50% of patients with VWD type 1 exhibit mutations in VWF. However, a large… read more here.
Keywords: methylation; vwf levels; low vwf; endothelial cells ... See more keywords
Single Cell Transcriptional Analysis of Human Endothelial Colony Forming Cells from Patients with Low VWF Levels.
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DOI: 10.1182/blood.2021010683
Abstract: Von Willebrand Factor (VWF) plays a key role in normal hemostasis and deficiencies of VWF lead to clinically significant bleeding. We sought to identify novel modifiers of VWF levels in endothelial colony forming cells (ECFCs)… read more here.
Keywords: cell; patients low; scrna seq; vwf ... See more keywords
Endothelial Colony Forming Cells from Individuals with Low VWF Levels Demonstrate Impairment in Stimulated VWF Release
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DOI: 10.1182/blood.v130.suppl_1.21.21
Abstract: Background Von Willebrand factor (VWF) is an essential hemostatic protein and deficiencies of VWF predispose to mucocutaneous bleeding (MCB) such as seen in von Willebrand disease (VWD). VWD type 1 is characterized by incomplete penetrance… read more here.
Keywords: vwf levels; low vwf; vwf release; individuals low ... See more keywords
Plasma VWF: Ag levels predict long-term clinical outcomes in patients with acute myocardial infarction
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DOI: 10.3389/fcvm.2022.1013815
Abstract: Background A vital role in coronary artery disease is played by Von Willebrand factor (VWF), which serves as a bridge between platelets and the subendothelial matrix after vessel damage. The purpose of the study was… read more here.
Keywords: plasma vwf; long term; vwf; vwf levels ... See more keywords
von Willebrand Factor Antigen Predicts Outcomes in Patients after Liver Resection of Hepatocellular Carcinoma
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DOI: 10.5009/gnl17115
Abstract: Background/Aims von Willebrand factor antigen (vWF-Ag) is a noninvasive predictor of portal hypertension that serves as a negative prognostic marker in various malignancies. Increased portal hypertension is associated with higher postoperative morbidity and decreased survival… read more here.
Keywords: vwf levels; liver resection; von willebrand; willebrand factor ... See more keywords