CTLA‐4‐expression on VZV‐specific T cells in CSF and blood is specifically increased in patients with VZV related central nervous system infections
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747079
Abstract: VZV‐reactivation may lead to symptomatic central nervous system (CNS) diseases, but identification of VZV as causative pathogen of CNS‐diseases is challenging. This study was performed to characterize VZV‐specific T cells from cerebrospinal fluid (CSF) and… read more here.
Keywords: vzv; specific cells; csf blood; vzv related ... See more keywords
Determinants of neurological syndromes caused by varicella zoster virus (VZV)
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DOI: 10.1007/s13365-020-00857-w
Abstract: Varicella zoster virus (VZV) is a pathogenic human herpes virus which causes varicella as a primary infection, following which it becomes latent in peripheral autonomic, sensory, and cranial nerve ganglionic neurons from where it may… read more here.
Keywords: zoster virus; virus vzv; vzv; neurological syndromes ... See more keywords
Negative IgG Varicella Zoster Virus Antibody Status: Immune Responses Pre and Post Re-immunization
Sign Up to like & getrecommendations! Published in 2017 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-017-0182-x
Abstract: IntroductionVaricella zoster virus (VZV) causes chicken pox and herpes zoster and is a self-limiting disease in healthy children. Vaccination is recommended for children, adolescents, and adults. This study discusses a healthy pediatric patient with negative… read more here.
Keywords: zoster virus; immunization; ige; igg ... See more keywords
Microfluidic electrical cell lysis for high-throughput and continuous production of cell-free varicella-zoster virus.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2021.06.006
Abstract: Varicella-zoster virus (VZV), the causative agent of varicella and herpes zoster, is highly cell-associated and spreads via cell-to-cell contact in tissue culture. The lack of cell-free VZV hampers studies on VZV biology as well as… read more here.
Keywords: electrical cell; cell lysis; vzv; cell free ... See more keywords
Prodrug Strategies for the Development of β-l-5-((E)-2-Bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-(dioxolane-4-yl))uracil (l-BHDU) against Varicella Zoster Virus (VZV)
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.3c00545
Abstract: Varicella zoster virus (VZV) establishes lifelong infection after primary disease and can reactivate. Several drugs are approved to treat VZV diseases, but new antivirals with greater potency are needed. Previously, we identified β-l-5-((E)-2-bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-(dioxolane-4-yl))uracil (l-BHDU, 1),… read more here.
Keywords: zoster virus; bromovinyl hydroxymethyl; virus vzv; vzv ... See more keywords
Herpetic Eye Disease Following the SARS-CoV-2 Vaccinations.
Sign Up to like & getrecommendations! Published in 2022 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2022.2103831
Abstract: PURPOSE To describe herpetic ocular infections following SARS-CoV-2 vaccinations. METHODS A retrospective study of herpetic ocular infections after BNT162b2mRNA vaccination and a literature review. RESULTS A cohort of five patients: three varicella zoster virus (VZV)… read more here.
Keywords: herpetic ocular; vzv; hsv; following sars ... See more keywords
Increased frequency of HLA-A*02 in patients with atherosclerosis is associated with VZV seropositivity
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Physiology and Biochemistry"
DOI: 10.1080/13813455.2019.1640253
Abstract: Abstract Background HLA molecules are inherited key molecules in the immune inflammation and specific responses to environmental pathogens. We investigated the association of HLA-A alleles with Varicella zoster virus (VZV) seropositivity in patients with atherosclerosis… read more here.
Keywords: vzv seropositivity; patients atherosclerosis; vzv; hla ... See more keywords
Varicella-zoster virus Neurovasculitis (VZV-NV) in the Setting of Autoantibodies to Interferon alpha (anti-IFNα)
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DOI: 10.1093/ofid/ofx163.716
Abstract: Abstract Background VZV-NV resulting in CNS damage is rare in immunocompetent hosts. Humoral immunity protects against acquiring VZV, and T-cell mediated immunity shields against reactivation of the latent virus. Individuals who are immunocompromised due to… read more here.
Keywords: vzv; csf; anti ifn; vzv setting ... See more keywords
VZV Presenting as Orbital Apex Disorder in an Immunocompetent Young Man: Neuromuscular Image.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuromuscular Disease"
DOI: 10.1097/cnd.0000000000000296
Abstract: Varicella zoster virus (VZV) (human herpesvirus 3) is a neurotropic double-stranded DNA virus, manifesting as varicella (chickenpox) at primary infection and herpes zoster (shingles) at recurrence. Prominent neurological complications of VZV reactivation include aseptic meningitis,… read more here.
Keywords: orbital apex; immunocompetent young; apex disorder; vzv ... See more keywords
Occurrence of Herpes Viruses in Morphologically Normal Corneas
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DOI: 10.1097/ico.0000000000002977
Abstract: Purpose: The purpose of this study was to detect the occurrence of herpes simplex virus (HSV) types 1 and 2 and varicella zoster virus (VZV) DNA in transplanted corneas using polymerase chain reaction (PCR) and… read more here.
Keywords: herpes viruses; occurrence herpes; vzv; hsv ... See more keywords
Identification and Characterization of CD4+ T Cell Epitopes after Shingrix Vaccination
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DOI: 10.1128/jvi.01641-20
Abstract: Understanding the T cell profile associated with the protection observed in elderly vaccinees following Shingrix vaccination is relevant to the general definition of correlates of vaccine efficacy. Our study enables these future studies by clarifying… read more here.
Keywords: shingrix vaccination; vaccination; identification; cell ... See more keywords