CTLA‐4‐expression on VZV‐specific T cells in CSF and blood is specifically increased in patients with VZV related central nervous system infections
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DOI: 10.1002/eji.201747079
Abstract: VZV‐reactivation may lead to symptomatic central nervous system (CNS) diseases, but identification of VZV as causative pathogen of CNS‐diseases is challenging. This study was performed to characterize VZV‐specific T cells from cerebrospinal fluid (CSF) and… read more here.
Keywords: vzv; specific cells; csf blood; vzv related ... See more keywords
Evaluation of Varicella‐zoster virus‐specific cell‐mediated immunity by interferon‐γ Enzyme‐Linked Immunosorbent Assay in adults ≥50 years of age administered a herpes zoster vaccine
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DOI: 10.1002/jmv.25391
Abstract: Varicella‐zoster virus (VZV)‐specific cell‐mediated immunity (CMI) is critical for preventing and controlling the onset of herpes zoster (HZ). To assess VZV CMI, an interferon‐γ (IFN‐γ) enzyme‐linked immunosorbent assay (ELISA) was validated by examining the influence… read more here.
Keywords: varicella zoster; cmi; vzv specific; vaccine ... See more keywords
Understanding the immunology of Shingrix, a recombinant glycoprotein E adjuvanted herpes zoster vaccine.
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DOI: 10.1016/j.coi.2019.02.009
Abstract: Herpes zoster is common in older and immune suppressed persons due to diminished VZV-specific cellular immunity. A recombinant herpes zoster vaccine (RZV) consisting of a single VZV glycoprotein and an adjuvant system stimulates robust and… read more here.
Keywords: zoster vaccine; herpes zoster; glycoprotein; immunology ... See more keywords