Glutamate Is a Wake-Active Neurotransmitter in Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2017 at "Sleep"
DOI: 10.1093/sleep/zsw046
Abstract: Introduction In mammals, there is evidence that glutamate has a role as a wake-active neurotransmitter. So using video-based analysis of Drosophila behavior, we undertook a study to examine if glutamate, which has been previously shown… read more here.
Keywords: wake active; active neurotransmitter; drosophila; glutamatergic neurons ... See more keywords
Galanin inhibition of wake-active histaminergic neurons
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733098
Abstract: Histaminergic neurons are a population of wake-active neurons confined to the tuberomammillary nucleus (TMN) in the posterior hypothalamus. They form a crucial component of the ‘sleep switch’ in the brain and promote arousal when activated.… read more here.
Keywords: hdc; galanin; histaminergic neurons; physiology ... See more keywords
A wake-active locomotion circuit depolarizes a sleep-active neuron to switch on sleep
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000361
Abstract: Sleep-active neurons depolarize during sleep to suppress wakefulness circuits. Wake-active wake-promoting neurons in turn shut down sleep-active neurons, thus forming a bipartite flip-flop switch. However, how sleep is switched on is unclear because it is… read more here.
Keywords: wake active; locomotion; neuron; ris ... See more keywords