Functional connectivity of the human hypothalamus during wakefulness and nonrapid eye movement sleep
Sign Up to like & getrecommendations! Published in 2021 at "Human Brain Mapping"
DOI: 10.1002/hbm.25461
Abstract: Animal experiments indicate that the hypothalamus plays an essential role in regulating the sleep–wake cycle. A recent neuroimaging study conducted under resting wakefulness conditions suggested the presence of a wake‐promoting region and a sleep‐promoting region… read more here.
Keywords: wakefulness; hypothalamus; connectivity; anterior hypothalamus ... See more keywords
Elucidation of Neural Circuits Involved in the Regulation of Sleep/Wakefulness Using Optogenetics.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-8763-4_25
Abstract: Although sleep is an absolutely essential physiological phenomenon for maintaining normal health in animals, little is known about its function to date. In this section, I introduce the application of optogenetics to freely behaving animals… read more here.
Keywords: wakefulness; circuits involved; neural circuits; sleep wakefulness ... See more keywords
Activation of ventral tegmental area dopamine neurons produces wakefulness through dopamine D2-like receptors in mice
Sign Up to like & getrecommendations! Published in 2017 at "Brain Structure and Function"
DOI: 10.1007/s00429-017-1365-7
Abstract: A growing body of evidence suggests that dopamine plays a role in sleep–wake regulation, but the dopamine-producing brain areas that control sleep–wake states are unclear. In this study, we chemogenetically activated dopamine neurons in the… read more here.
Keywords: wakefulness; tegmental area; dopamine; ventral tegmental ... See more keywords
Paraventricular Thalamus as A Major Thalamic Structure for Wake Control
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-019-00364-x
Abstract: The thalamus is the gate of the cerebral cortex, the ultimate target for the neural networks controlling behavioral states and cognitive functions. According to the reticular theory initially proposed by Moruzzi and Magoun, excitatory inputs… read more here.
Keywords: wake control; wakefulness; cortical activation; thalamus ... See more keywords
Linking the nature and functions of sleep: insights from multimodal imaging of the sleeping brain
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Physiology"
DOI: 10.1016/j.cophys.2019.11.012
Abstract: Sleep and wakefulness are traditionally considered as two mutually exclusive states with contrasting behavioural manifestations and complementary neurobiological functions. However, the discoveries of local sleep in global wakefulness and local wakefulness in global sleep have… read more here.
Keywords: wakefulness; sleeping brain; nature functions; multimodal imaging ... See more keywords
Theta waves in children’s waking electroencephalogram resemble local aspects of sleep during wakefulness
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11577-3
Abstract: Vyazovskiy and colleagues found in rats’ multi-unit recordings brief periods of silence (off-states) in local populations of cortical neurons during wakefulness which closely resembled the characteristic off-states during sleep. These off-states became more global and… read more here.
Keywords: wakefulness; local sleep; theta; theta waves ... See more keywords
Two distinct ways to form long-term object recognition memory during sleep and wakefulness
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2203165119
Abstract: Significance Long-term memories are considered to be optimally formed during sleep, but they may also be formed during wakefulness. Using behavioral indicators dissociating object and context memory in a novel-object recognition (NOR) paradigm, in combination… read more here.
Keywords: long term; consolidation; object recognition; memory ... See more keywords
CREB is Required in Excitatory Neurons in the Forebrain to Sustain Wakefulness.
Sign Up to like & getrecommendations! Published in 2020 at "Sleep"
DOI: 10.1093/sleep/zsaa267
Abstract: The molecular and intracellular signaling processes that control sleep and wake states remain largely unknown. A consistent observation is that the cyclic-AMP response element binding protein (CREB), an activity-dependent transcription factor, is differentially activated during… read more here.
Keywords: sleep wake; creb required; wakefulness; creb ... See more keywords
Heart Rate Variability during Wakefulness as a Marker of Obstructive Sleep Apnea Severity.
Sign Up to like & getrecommendations! Published in 2021 at "Sleep"
DOI: 10.1093/sleep/zsab018
Abstract: STUDY OBJECTIVES Patients with obstructive sleep apnea (OSA) exhibit heterogeneous heart rate variability (HRV) during wakefulness and sleep. We investigated the influence of OSA severity on HRV parameters during wakefulness in a large international clinical… read more here.
Keywords: domain; sleep apnea; hrv; wakefulness ... See more keywords
Neurotransmitters of sleep and wakefulness in flatworms.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsac053
Abstract: STUDY OBJECTIVES Sleep is a prominent behavioral and biochemical state observed in all animals studied, including platyhelminth flatworms. Investigations into the biochemical mechanisms associated with sleep - and wakefulness - are important for understanding how… read more here.
Keywords: neurotransmitters sleep; effect; wakefulness; sleep wakefulness ... See more keywords
Histaminergic neurons in the tuberomammillary nucleus as a control centre for wakefulness
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15220
Abstract: Histamine plays pleiotropic roles as a neurotransmitter in the physiology of brain function, this includes the maintenance of wakefulness, appetite regulation and memory retrieval. Since numerous studies have revealed an association between histaminergic dysfunction and… read more here.
Keywords: brain histamine; wakefulness; histaminergic neurons; control ... See more keywords