The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-025-10059-w
Abstract: Otto Warburg originally proposed that cancer arose from a two-step process. The first step involved a chronic insufficiency of mitochondrial oxidative phosphorylation (OxPhos), while the second step involved a protracted compensatory energy synthesis through lactic… read more here.
Keywords: warburg hypothesis; cancer; production; oxygen consumption ... See more keywords